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1 Monday – May13th, 2019

Programa Multicêntrico de Pós-Graduação da SBBq

10:00 am to 12:00 pm - Room Opala Reunião com os Coordenadores locais e Embaixadores 02:00 pm to 05:00 pm – Room Opala Reunião do Colegiado Geral

Tuesday – May14th, 2019

Programa Multicêntrico de Pós-Graduação da SBBq 08:00 am to 12:00 pm - Room Diamante

Apresentação Oral dos Alunos do Programa

8:00 Nitric Oxide Inhibition in Rhodium/HPβCD Treated RAW264.7 and J774.A1 Macrophages Paloma Esteves de Carvalho, UFJF

8:20

Quercetin Treatment Restores Antioxidant Activity and Blocks H2O2 Production in Isoproterenol-Induced Cardiac Hypertrophy

Joana Varlla de L. Alexandre, UFCA

8:40 Isoobtusilactone A leads to lipid imbalance in Trypanosoma cruzi Júlio Menta de Almeida, UFMS

9:00

Assessment of Astrocytic and Neuronal Response Mechanisms by Exposure to OGN/OGD or Glutamatergic Excitotoxicity and the Possible Neuroprotective Effects of EDAC.

Rafael Short Ferreira, UFBA

9:20

Investigating the Association Between Ascidian Sulphated Glycosaminoglycans and Trace Elements in Tumor Progression

Ananda de Araújo Bento, IFRJ

9:40

Key amino acid residues that interact with glucose-6-phosphate and improve the enzymatic activity of β- glucosidase

Anderson Albino Gomes, UDESC

10:00

Optimization of Pigment Production by Rhodotorula minuta, through Submerged Fermentation Using Yellow Passion Fruit Bark

Thamilly Moreira Silva, UESB 10:20-10:40 Intervalo

10:40 FXYD2, a possible cardiotonic steroids effects modulator in cell biology Ana Carolina Pacheco Ramos, UFSJ

11:00 Igy immunoglobulin recognition by a bifunctional chimeric recombinant protein Lina Maria S. Echeverri, UDESC

11:20 The conformation of the N-terminal of the Prion Protein is Important to Direct Its Route of Aggregation Cyntia Alves Conceição, IFRJ

11:40

Structural and Functional Evaluation of an Alpha-helical Peptide with Antimicrobial Activity Designed with Computational Assistance

Claudiane Vilharroel Almeida, UFMS

12:00

Identification of immunological, nutritional, parasitological/serological parameters in a case-control study associated with leprosy.

Lorena Bruna P. de Oliveira, UFJF

12:20

Caloric Restriction Improves Oxidative Stress and Mitochondrial K+ Entrance on Isoproterenol-Induced Cardiac Hypertrophy

Cícera Edna Barbosa David, UFCA Programa Multicêntrico de Pós-Graduação da SBBq 02:30 pm to 5:00 pm - Room Diamante

Reunião Geral com Coordenadores locais, Embaixadores Docentes e Discentes do PMBqBM

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Tuesday – May14th, 2019 1:00 to 5:00 pm - Courses Room Ametista

Curso 1: Ciência da Cerveja: Princípios Teóricos e Práticos (Beer Science: Theoretical and Practical Principles) Responsável: Prof. Dr. Gabriel Hornink, Unifal, MG

Room Turmalina

Curso 2: Usando Análises de Famílias de Proteínas para Planejar Experimentos in vitro, in vivo e in silico Responsável: Prof. Dr. Lucas Bleicher, UFMG

Room Topázio

Curso 3: Simulação Computacional de Biomoléculas

Responsável: Prof. Dr. Guilherme Menegon Arantes, IQ-USP

2:00 to 06:00 pm

Room Pentágono: Registration

4:30 to 5:00 pm

Room Pentágono: Coffee Break with Exhibitors

5:00 to 5:30 pm

Room Esmeralda: Opening Ceremony 5:30 to 6:30 pm

Room Esmeralda: Opening Conference Chair: Selma Jeronimo (UFRN)

Nutrient Regulation of Transcription & Signaling by O-GlcNAc

Gerald W. Hart

University of Georgia, USA

6:30 to 8:30 pm

Room Pentágono: Welcome cocktail

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48th Annual Meeting of SBBq - 3

Wednesday – May 15th, 2019

8:30 am to 10:30 am – Room Esmeralda 8:30 am to 10:30 am – Room Diamante SP.1: Systems Biology and Biomarkers for Human Disorders

Chair: Daniel Martins-de-Souza (IB-UNICAMP)

SP.2: Molecular Control of Mitochondrial Biogenesis by Nuclear Receptor Co-Regulators

Chair: Leonardo R. Silveira (IB-UNICAMP) Unraveling the proteomics landscape of cancerous and non-

cancerous tissues

Priscila Ferreira Aquino, FIOCRUZAmazonia, AM, Brasil

Molecular profiling of murine melanoma progression identifies independent prognostic factors for melanoma patients

Miriam Galvonas Jasiulionis, UNIFESP, SP, Brasil

Neuronal gene expression as possible biomarkers for autism spectrum disorders

Karina Griesi Oliveira, Hosp. Albert Einstein, SP, Brasil

Characterization of clinically-relevant Cancer/Testis (CT) genes

Sandro José de Souza, UFRN, RN, Brasil

Nuclear Receptors, Co-Activators and Exercise Mimetics:

Road to Medicine or Sports Doping Gone Awry

Vihang A.Narkar, The University of Texas Health Science, Houston, Texas, USA

Mitochondrial (dys)function: a double-edge sword in cell death and survival

Nicoletta Guaragnella, University of Bari-Italy, Italy

Looking for new molecular mechanisms of obesity and diabetes, through phosphorylation and repression of PPAR gama

Ana Carolina F. Migliorini, LNBio – Campinas, SP, Brasil PPAR coregulators are essential mediators of

mitochondrial function and redox homeostasis in skeletal muscle cells

Leonardo R. Silveira, IB-UNICAMP, SP, Brasil

8:30 am to 10:30 am – Room Topázio 8:30 am to 10:30 am – Room Turmalina SP.3: Rational design of fungal cell factories for enzymes

production

Chair: André R.L. Damasio (IB-UNICAMP)

SP.4: 23 Young Talent Prize in Life Science (SBBq and GE Healthcare)

Chair: Luiz Bezerra de Carvalho Jr (UFPE) Using CRISPR/Cas9 to construct Fungal Cell Factories

Uffe H. Mortensen, Technical University of Denmark, Lyngby, Denmark

Transcriptional factor engineering in Trichoderma reesei to improve cellulase production

Roberto do Nascimento Silva, FMRP-USP, RP, Brasil N-glycosylation and enzymes secretion in Aspergillus nidulans

André R.L. Damasio, IB-UNICAMP, SP, Brasil Mining and design of novel expression systems in filamentous fungi and yeast though synthetic biology Rafael Silva Rocha, FMRP-USP, RP, Brasil

The Regulatory Role of NF-kappaB and Twist1 in Breast Cancer Cells

Bruno Ricardo Barreto Pires, INCA-RJ, RJ, Brasil Salt Stress Modulates the Dynamics, Structure and Architecture of Plant Cell Walls

Dyoni Matias de Oliveira, UEM, PR, Brasil

Methylphenidate alters Akt-mTOR signaling in rat pheochromocytoma cells

Felipe Schmitz, UFRGS, RS, Brasil

Acute and chronic neurological consequences of neonatal Zika virus infection in mice

Isis Nem de Oliveira Souza, UFRJ, RJ, Brasil

Autophagy activation is required for high-fat diet-induced mitochondrial metabolic changes in skeletal muscle Pablo Esteban Morales, Univ. de Chile, Chile

10:30 am to 11:00 am – Coffee Break

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Wednesday – May 15th, 2019

11:00 am to 12:00 pm – Room Esmeralda 11:00 am to 12:00 pm – Room Diamante

Conference 1 Conference 2

Chair: Leda Q. Vieira (UFMG) Chair: Maria Luiza Vilela Oliva (UNIFESP) Exploring the content of noncoding RNAs in the protozoan

parasite Leishmania

Extracellular cysteine cathepsins: targets for diagnostics and therapy in cancer

Angela K. Cruz, FMRP-USP Boris Turk, Jožef Stefan Institute, Slovenia 11:00 am to 12:00 pm – Room Topázio

Conference 3

Chair: Aline Maria da Silva (IQ-USP) Assisted cell death in prostate regression

Hernandes F. Carvalho, UNICAMP-IB 12:00 pm to 1:30 pm – Lunch

Wednesday – May 15th, 2019

1:45 to 3:45 – Room Esmeralda 1:45 to 3:45 – Room Diamante SP.5: Biochemistry of skin cells under sun light (SBBf-SBBq)

Chair: Maurício Baptista (IQ-USP)

SP.6: Uruguay-Brazil Symposium: Redox Processes in Healthy and Disease

Chair: Flavia Meotti (IQ-USP) Redox-directed Molecular Strategies for Skin

Photoprotection, Cancer Photochemoprevention, and Chemotherapeutic Intervention.

Georg T. Wondrak, The University of Arizona Cancer Center, Tucson, USA

Understanding UVA light deleterious effects in human cells from patients defective on DNA damage responses

Carlos Menck, ICB-USP, SP, Brasil

Impact of sunlight exposure upon tadpole skin and ecology:

focus on the genotoxic stress

André Passaglia Schuch, UFSM, RS, Brasil

Malignant transformation of keratinocytes chronically exposed to visible light

Mauricio Baptista, IQ-USP, SP, Brasil

Monitoring redox changes in living trypanosomatid pathogens using a genetically-encoded biosensor Marcelo Comini, Institute Pasteur, Montevideo, Uruguay

Biological Chemistry of Hydrogen Sulfide and Persulfides Beatriz Alvarez, UDeLaR- FCF, Montevideo, Uruguay

FSP1 is a glutathione-independent ferroptosis suppressor José Pedro Friedmann Angeli, University of Würzburg, Würzburg, Germany

The labile iron pool (LIP) reacts rapidly and catalytically with peroxynitrite and attenuates oxidation of intracellular targets

José Carlos Toledo Junior, FFCLRP-USP, RP, Brasil

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48th Annual Meeting of SBBq - 5

Wednesday – May 15th, 2019

01:45 to 3:45 pm – Room Topázio 1:45 to 3:45 pm - Room Turmalina SP.7: Computational Simulations for Drug Design from

Different Aspects

Chair: Ana Ligia Scott (CMCC - UFABC)

SP.8: Analysis and genetic modification of yeasts for industrial applications

Chair: Anderson Ferreira da Cunha (CCBS -UFSCAR) Ligand-based approaches and the employment of machine

learning techniques in the discovery of new antibacterial agents

Vinicius G. Maltarollo, UFMG, MG, Brasil Ligand-Dependent Macromolecular Structural Rearrangements - A Free Energy View

Alessandro S. Nascimento, USP- IFSC, SP, Brasil

Loss-of-function in HSP70 causes pathological mitophagy in Parkinson’s disease and holds the key to new therapeutic strategies

Fillipo Pullara, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA

Protein-Ligand and Protein-protein Docking considering global and local conformational changes: some studies cases.

Ana Ligia Scott, Universidade Federal do ABC, SP, Brasil

Development of superior industrial yeast strains for first- and second-generation bioethanol production

Johan Thevelein, Univ Católica de Leuven, Leuven, Belgium

Cachaça yeast strains for biotechnological applications Rogelio L. Brandão, UFOP, MG, Brasil

Design of microbial cell factories for renewable fuels Leandro V. dos Santos, CTBE-CEPEM

Brettanomyces: trying to understand their ability to adapt to stress conditions

Angélica Ganga Muños, Universidade de Santiago, Santiago, Chile

3:45 to 4:30 pm: Coffee break with Exhibitors

4:30 pm to 6:30 pm: Poster Session - Odd Numbers (números ímpares)

6:30 pm to 7:30 pm

Room Esmeralda: Workshop: How to publish in JBC JBC editorial board members:

Gerald Hart Gustavo Salinas Beatriz Alvarez Courses

6:30 pm to 7:30 pm – Room Topázio

Course 2: Usando análises de famílias de proteínas para planejar experimentos in vitro, in vivo e in silico Responsável: Prof. Dr. Lucas Bleicher, UFMG

6:30 pm to 8:30 pm – Room Turmalina

Course 3: Simulação Computacional de Biomoléculas Responsável: Prof. Dr. Guilherme Menegon Arantes, IQ-USP 8:45 pm to 10:00 pm – Room Turqueza

SBBq Council Meeting

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Thursday – May 16th, 2019

08:30 to 10:30 am – Room Esmeralda 08:30 to 10:30 am – Room Diamante SP.9: Metabolismo Energético

Chair: Marcelo Mori (UNICAMP)

SP.10: Avanços da Entomologia Molecular Chair: Fernando Ariel Genta (FIOCRUZ/RJ) Calorie restriction and aging: the mitochondrial connection

Alicia Kowaltowski, IQ-USP, SP, Brasil

Mitochondrial metabolism in the biology insect vectors of tropical diseases

Marcus F. Oliveira, UFRJ, RJ, Brasil Fine tuning of adipocyte functionality

Brice Emanuell, University of Copenhagen, CBMR, Copenhagen, Denmark

Role of NAMPT and NAD+ precursors for skeletal muscle health and disease

Jonas Treebak, University of Copenhagen, CBMR, Copenhagen, Denmark

Transcriptional profile of culex quinquefasciatus highly resistant to Lysinibacilllus sphaericus biolarvicide reveals new genes and pathways involved with this phenotype Maria Helena Silva-Filha, IAM-FIOCRUZ/PE, PE, Brasil Functional genomic tools in the identification of new genes and regulatory elements in non-model arthropods

Rodrigo Nunes da Fonseca, UFRJ-Macaé, RJ, Brasil Prospection of repellents for the Chagas disease vector, Rhodnius prolixus, which is refractory to DEET

Ana Claudia do Amaral Melo, UFRJ-IQ, RJ, Brasil

A novel midgut pseudo-aspartic peptidase from the tick Rhipicephalus microplus

Aparecida Tanaka, UNIFESP, SP, Brasil

08:30 to 10:30 am – Room Topázio 08:30 to 10:30 am – Room Turmalina SP.11: SBBf-SBBq Brazil-Portugal Symposium: Membrane-

biomolecules interaction mechanisms Chair: Rosangela itri (IF-USP)

SP.12: Simpósio SBBq Conesul: Young Scientist Platform Session I

Chair: Maria de Fátima Dias Costa (UFBA) The hydrophobic pulmonary surfactant proteins SP-B and

SP-C in interaction with membranes: topology, lipid selectivity and homo and hetero-oligomerization Manuel Prieto, Instituto Tecnico Superior, Univ Lisboa, Lisbon, Portugal

Molecular mechanisms of bile-acid induced apoptosis and cytoprotection

Nuno Bernardes, Instituto de Bioengeneering and Bioscience, Univ Lisboa, Lisbon, Portugal

Surface Assessment via Grid Evaluation (SuAVE): A Tool to Analyze Curvature-Dependent Properties in Membranes Thereza A. Soares da Silva, UFPE, PE, Brasil

Bringing disorder to order: new insights into the structure- function correlation of the Golgi Reassembly and Stacking Proteins

Antonio Jose da Costa Filho, FFCLRP-USP, RP, Brasil

NO and H2O2 are signaling molecules early involved in cardiac mitochondrial dysfunction observed in Type 1 Diabetes mellitus

Ivana A. Rukavina-Mikusic, Univ. de Buenos Aires, , Argentina

The estrogen signaling coactivator ART-27/UXT-V2 is a canonical E3 ubiquitin-ligase SCF(Fbxo7) substrate Valentine Spagnol, UFSCAR, SP, Brasil

MicroRNAs in Glioblastoma; Role Played by the Hypoxia Microenvironment

Lucy W. Macharia, UFRJ, RJ, Brasil

CDC42 as an epigenetic regulator of ID4 in breast cancer Daniela L. Nasif, National University of Cuyo, Argentina Genomic analysis of two parasite strains isolated from a fatal case of visceral Leishmaniasis

Talita Y. Takahashi, UFSCAR, SP, Brasil 10:30 am to 11:00 am – Coffee Break

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7 Thursday – May 16th, 2019

11:00 am to 12:00 pm – Room Esmeralda 11:00 am to 12:00 pm – Room Diamante

Conference 4 Conference 5

Chair: Emanuel M. de Souza (UFPR) Chair: Aparecida S. Tanaka (UNIFESP) Plant microbiota assembly and functions in plant growth

and health

Recombinant antibody library displayed on phage surface

Paul Schulze-Lefert, Max Planck Institute for Plant Breeding Research

Michael Hust, Technische Universität Braunschweig

11:00 am to 12:00 pm – Room Topázio Conference 6

Chair: José Ribamar dos Santos Ferreira Júnior, EACH USP Mitochondria-cytosol-nucleus crosstalk: learning from Saccharomyces cerevisiae

Sergio Giannattasio, Inst. of Biomembranes, Bioenergetics and Mol. Biotechnologies, Italy

12:00 pm to 1:30 pm – Lunch

1:45 to 3:45 pm – Room Esmeralda 1:45 to 3:45 pm – Room Diamante SP.13: The challenges in doing Science off the beaten track

Chair: Richard C. Garratt (IFSC-USP)

SP.14: Neurodegeneration Chair: Elis Eleutherio (UFRJ) Sirius: The New Brazilian Synchrotron Light Source

Antonio Jose Roque da Silva, LNLS, SP, Brasil

Structural studies on carbonic anhydrases: the first protein crystallography project in Jordan

Areej Abuhammad, University of Jordan, Amman, Jordania A Brighter light for African Science – The African Light Source Project

Simon H. Connell, School of Physics, University of Johannesburg, Johannesburg, South Africa

Structures of Biological Macro-molecules by Single-Particle Cryo-EM: The roots of the “resolution revolution”

Marin Van Heel, LNNano, SP, Brasil

Structure dynamics and kinetics of folding and recognition in proteins by NMR

Christian Griesinger, Max Planck Inst. For Biophysical Chemistry, Göttingen, Germany

Functional links between Sod1 mutants, oxidative stress and Amyotrophic Lateral Sclerosis risk factors

Elis Eleutherio, UFRJ, RJ, Brasil

Alpha-synuclein acts in the nucleus and deregulates gene expression: insight into the molecular basis of Parkinson's disease

Tiago Fleming Outeiro, Georg-August-Universität Göttingen, Germany

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Thursday – May 16th, 2019

1:45 to 3:45 pm – Room Topázio 1:45 to 3:45 pm - Room Turmalina SP.15: Editorial Polices, pear review and open access

Chair: Abel Packer (Scielo)

SP.16: Simpósio SBBq Conesul: Young Scientist Platform Session II

Chair: Maria Tereza Correia (UFPE) To be announced

Gerald W. Hart, University of Georgia (Ed. JBC), USA Traditional vs open access journals and the quality of scientific manuscripts

Alexander Wlodawer, NIH (PLoS ONE e FEBS Open Access), USA

Research Data Management and Sharing: concepts, international and Brazilian initiatives

Fátima L. S. Nunes, EACH-USP, SP, Brasil

Preprint and open peer review: immediate access and transparency in the publication of scientific results.

Adeilton Brandão, FIOCRUZ(Memórias do Instituto Oswaldo Cruz), RJ, Brasil

Frataxin as the Source of Ferrochelatase Activity in Plant Mitochondria

Alejandro Armas, Universidad Nacional de Rosario, Argentina

Structural study of CAMKK1 and inhibitor identification André S. Santiago, UNICAMP, SP, Brasil

Cramoll and BmoLL Lectins Conjugated to Quantum Dots for Glycobiological Studies

Weslley F. de Oliveira, UFPE, PE, Brasil

Calorimetric analysis of the interactions between SDS and the catalytic domain of a thermophylic Cu(I) transport ATPase

Alvaro A. Recoulat Angelini, Univ. de Buenos Aires, Argentina

Effect of light on the physiological characteristics of Ralstonia pseudosolanacearum during the colonization of tomato plants.

Maria Josefina Tano, Instituto de Biología Molecular y Celular de Rosario-CONICET, Argentina

3:45 to 4:30 pm: Coffee Break with Exhibitors

04:30 to 6:30 pm: Poster Session - Even Numbers (números pares) 06:30 to 7:30 pm Room Turmlina

Course 2: Usando análises de famílias de proteínas para planejar experimentos in vitro, in vivo e in silico Responsável: Lucas Bleicher, UFMG

06:30 to 7:30 pm: Room Esmeralda

General Assembly (Portuguese). All participants are invited.

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9 Friday – May 17th, 2019

08:30 to 10:30 am – Room Esmeralda 08:30 to 10:30 am – Room Diamante SP.17: Plant Associated Microbiome

Chair: Fabio Oliveira Pedrosa (UFPR)

SP.18: Biochemistry and Molecular Biology of Enzymes from Natural Products Biosynthesis.

Chair: Marcio Dias (ICB-USP) Crop Microbiome: From Field to Computer and Back

Leonardo M. Cruz, UFPR, PR, Brasil

Biodiversity of plant growth promoting rhizobacteria in Brazilian soils: advances and chalenges

Fatima Maria de Souza Moreira, UFLA, MG, Brasil Stable Isotope Probing coupled with G+C fractionation technique can identify active microbial communities involved in the 13C-CH4 biogeochemical cycle in tropical soils

Siu Mui Tsai, CENA, SP, Brasil

Exploring the mechanisms by which rhizosphere bacteria promote plant growth

Gary Stacey, National Center for Soybean Biotechnology, University of Missouri, Columbia, MO, USA

Disentangling natural products of Brazilian Cyanobacteria Marli de Fátima de Fiori, ESALQ-USP, SP, Brasil

Insights into the function of natural products in the Penicillium digitatum – citrus interaction

Taícia Fill Pacheco, UNICAMP, SP, Brasil

Aminoglycoside gentamicins: from Understanding to Creating

Yuhui Sun, Wuhan University School of Pharmaceutical Sciences, Wuhan, China

Chemical probing of antibiotic biosynthetic pathways Manuela Tosin, University of Warwik, Coventry, UK

08:30 to 10:30 am – Room Topázio 08:30 to 10:30 am– Room Turmalina SP.19: Promoting the divulgation of teaching and research

in Biochemistry and Molecular Biology Chair: Vera M.T. Trindade (UFRGS)

SP.20: Advances in Basic Research Translated Into Patient Care

Chair: Ivarne Tersariol (UNIFESP) Divulgation of digital didactic material: experiences and

impact of different platforms

Eduardo Galembeck, UNICAMP, SP, Brasil

The electronic magazine “A Bioquímica como ela é “ as learning tool in science communication to the general public.

José Claudio Fonseca Moreira, UfRGS, RS, Brasil Journal of Biochemistry Education: disseminating and encouraging the production in Biochemistry and Molecular Biology Education

Gabriel G. Hornink, Unifal, MG, Brasil

Challenges in structural analyses of carbohydrates in glycobiology

Guilherme L. Sassaki, UFPR, PR, Brasil

Expression of o-glycosylated oncofetal fibronectin in m2- like differentiated human macrophages

Leonardo Freire de Lima, UFRJ, RJ, Brasil

Proteoglycans, Glycosaminoglycans and Proteases: Role and Function on Dentin Matrix

Fabio D. Nascimento, UMC, SP, Brasil

Heparin Oligosaccharides as a New Class of Antiarrhythmic Drug

Ivarne Tersariol, UNIFESP

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10:30 am to 11:00 am Coffee break

11:00 am to 12:00 pm – Room Esmeralda 11:00 am to 12:00 pm – Room Diamante

Conference 7 Conference 8

Chair: Maria Elena de Lima, UFMG Chair: Fabio Pedrosa, UFPR

The complex enzymology of the endocannabinoid system Using Synthetic Biology to Engineer Nitrogenase in Eukaryotes

Stephen Alexander, Nottingham University, UK Luis Rubio, Universidad Politécnica de Madrid 11:00 am to 12:00 pm – Room Topazio

Conference 9

Chair: Hugo Verli, UFRGS

On the hunt for precursors of amyloid fibers: a walk through the denaturation pathways of immunoglobulin domains

Carmen Nina Pastor Colón, Universidad Autónoma del Estado de Morelos, Mexico

12:00 to 1:30 pm Lunch

1:45 to 3:45 pm – Room Esmeralda 1:45 to 3:45 pm – Room Diamante SP.21: Structural Proteomics

Chair: Tatiana Brasil (ICC, FIOCRUZ-PR)

SP.22: Argentina-Brasil Symposium: Signal transduction and defense in plants

Chair: Marcio Ramos (UFC) Molecular Architecture of the Antiophidic Protein Dm64

and its Complex with Myotoxin II from Bothrops asper Venom

Ana Gisele da C. Neves Ferreira, Fiocruz-RJ, RJ, Brasil Glycoproteins in infectious diseases: mass spectrometry- based analytical approaches and functional aspects Giuseppe Palmisano, ICB-USP, SP, Brasil

The cross-talk between the metalloproteinase ADAM17 and the thiol reductase Thioredoxin

Daniela Campos Granato, LNBio – Campinas, SP, Brasil Structure determination of neurodegenerative disease- related misfolded protein aggregates by short-distance crosslinking constraint-guided discrete molecular dynamics (CL-DMD)

Christoph Borchers, Univ of Victoria, Canada

Plant Natriuretic Peptides in Plant-Pathogen Interactions Jorgelina Ottado, Univ. Nac de Rosário, Rosário, Argentina Regulation of auxin signaling: A key node of plant

development and acclimation to stress.

Claudia Casalongue, Univ. Nac. de Mar del Plata, Argentina Transcriptional profile of two Herbaspirillum species associated to Poaceae.

Emanuel Maltempi de Souza, UFPR, PR, Brasil Laticifers, Latex and Their Role in Plant Defense Marcio V. Ramos, UFC, CE, Brasil

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48th Annual Meeting of SBBq - 11

1:45 pm to 3:45 pm – Room Topázio 1:45 pm to 3:45 pm – Room Turmalina SP.23: Chile-SBBq Symposium: Signaling and molecular

mechanisms of metabolic stress in human diseases Chair: Marcelo Damário (FMRP-USP)

SP.24: Allergy, Knowing and presenting solutions.

Characteristics of allergens, new preventive and therapeutic approaches

Chair: Olga Lima Tavares Machado (UENF) Polycystin-2, a new player in the autophagy machinery

Alfredo Criollo, Univ. de Chile

A novel function of the unfolded protein response (UPR) sensor IRE1α in the control of cell migration: implications into human diseases.

Hery Urra, Univ de Chile

A role for brown fat secreted lipokines in glucose metabolism

Luis Osório Silveira Leiria, UNICAMP, SP, Brasil cAMP as a new anabolic stimuli on muscletrophicity Luis Carlos Carvalho Navegantes, FMRP-USP, SP, Brasil

Food allergy immunotherapies: different strategies to control the mucosal inflammation

Guillermo H. Docena, Univ. Nacional de La Plata, Buenos Aires, Argentina

Mutant recombinant hypoallergenic Protein Derivative of ricinus communis: allergen (mrric c 1) for allergen-specific Immunotherapy

Thais Pacheco Soares, UENF, RJ, Brasil

3:45 to 4:15 pm: Coffee break 4:30 to 5:30 pm: Closing Lecture Room Esmeralda

Chair: Alicia J. Kowaltowski (IQ-USP)

Mitochondria in Life and Death: Mammalians, Plants, Fungi and Trypanosomes Anibal E. Vercesi

UNICAMP

Prize SBBq-Leopoldo de Meis

5:30 to 6:30 pm: Closing Ceremony Room Esmeralda

The announcements of SBBq Awards for:

23

th

GE Healthcare-SBBq Prize for Young Talent in Life Sciences

Bayardo B. Torres National Award for Teaching Biochemistry and Molecular Biology

Best Poster Presentation

FUNDAPE Prize (Best poster in Molecular Biology presented by a graduation student)

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Poster Session

Please set up your poster up on Tuesday (May 14th) between 2:00 and 6:30 pm and take it down on Friday (May 17th) until 5 pm

Authors must be available for poster discussion between 4:30 to 6:30 pm on:

Wednesday (May 15th): Odd Numbers (números ímpares) Thursday (May 16th): Even Numbers (números pares)

Young Talent Symposium participants will present posters on Wednesday (May 15th) Conesul Symposium participants will present posters on Thursday (May 16th)

Technical Seminars

May 15th, 2019 - Wednesday

Agilent Room: Rubi

09:00 am The importance of methods for sample quality control in multiple experimental scenarios Speaker: Elisabete Miracca – Genomics Product Specialist

09:50 am Integrated Biology analysis as an Improved way to early detect molecular alteration in cancer diseases and to identify cancer biomarkers

Speaker: Mauricio Marques - LCMS Product Specialist

10:40 am Consumables solution in liquid chromatography for Bio applications Speaker: Mariana Baptistão – CSD Application Scientist

11:30 am Question and Answer Session

Illumina Room: Turquesa

02:00 – 03:00 pm Delivering New Capabilities on Illumina Sequencers, from iSeq™ to NovaSeq™ Palestrante: Dr.

Daniella Rossetto

03:00 – 04:00 pm Profiling the microbiome using Illumina NGS Palestrante Dr Nelson Alves Junior.

04:00 – 05:00 pm Discuss your project! - Illumina in-person Technical Support

BD Room: Âmbar

02:00 – 04:00 pm Flow Cytometry and Multiomics: Helping aswering your questions Speaker: Lucas Rizzo – Especialista de Aplicação de campo

Kasvi Room: Rubi

02:00 – 03:30 pm Best Practices in Microscopy

Speaker: Anderson Silveira - Biomedical and scientific advisor at Kasvi with more than 8 years of experience in microscopy

04:30 – 06:00 pm Best Practices in Microscopy

Speaker: Anderson Silveira - Biomedical and scientific advisor at Kasvi with more than 8 years of experience in microscopy

Optical microscopy, Techniques of microscopy, Adjustments and caution with the microscope * Limited registration at Kasvi booth.

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May 16th, 2019 - Thursday

GE Room: Rubi

09:30 – 10:30 am How to improve your purification protocol

Significant improvements can be achieved in your protein purification workflow with small changes or new technologies. In this presentation, we will share tips for success chromatography and how ÄKTA™

systems with new applications and our modern resins can help your protein purification. – Speaker: Fellipe Bronze | Scientific Advisor | Sinapse Biotecnologia

11:00 – 12:00 pm Automated multistep purification using ÄKTA™ chromatography systems

To save time and increase efficiency, many scientists consider increase the level of automation in their protein purification workflows. Automated multistep workflows can vary in sophistication depending on objective and resources available. In this presentation we will learn more about how to utilize

automation capabilities in ÄKTA™ systems and UNICORN™ software.

Speaker: Rafael Santos | Product Specialist | GE Healthcare Life Sciences 02:00 – 04:00 pm Who wanna a successful western blotting?

How to achieve the best results in your western blotting process? Discover the complete solution offered by GE Healthcare for this technique, providing quality results and consequently great success in the final result

Speaker: Melissa Armelini, PhD | Product Specialist | GEHC Life Sciences

Merck Room: Opala

09:00 – 10:00 am Duolink: Protein/protein interaction assessment through proximity ligation assay Speaker: Paola Braga

10:30 – 12:00 am Essential tools for lipidomics – overview, launches and troubleshooting – Speaker: Misael Silva e Bruna Cassanho

10:30 – 12:00 am How to speed up your Western Blot Assays Speaker: Misael Silva

04:30 – 05:30 pm Innovation in Liquid Chromatography – Core Shell particles technology for proteomics Speaker: Amanda Baumgartner

Greiner Bio-One Room: Turquesa

09:30 – 10:30 am Magnetic 3D Bioprinting applied to High-Throughput Screening Platform to Advance Cancer Research

Speaker: Angélica Silveira, PH.D.

10:30 – 11:00 am Coffee Break

14:00 – 15:00 pm Magnetic 3D Bioprinting applied to High-Throughput Screening Platform to Advance Cancer Research

Speaker: Angélica Silveira, PH.D.

Hexis Room: Âmbar

09:30 – 10:20 am Bio-Layer Interferometry (BLI) Technology: real-time analysis of biomolecular interactions Speaker: LUCIANE GANIKO, PhD | Application Consultant

04:00 – 04:50 pm Bio-Layer Interferometry (BLI) Technology: real-time analysis of biomolecular interactions Speaker: LUCIANE GANIKO, PhD | Application Consultant

Leica Room: Âmbar

Progressa Room: Amistita

02:00 pm Pipetting technics: Choose the best pipetting technique and have the most reproducible results Speaker: Josely Chiarella

03:00 pm Long life for your pipette: how to do a quick inspection and preventive maintenance in your own lab

Speaker: Josely Chiarella

04:00 pm What can be automated in your lab? Easy and simple automation can maximize the

reproducibility of your sample preparation and accelerate your results Speaker’: Josely Chiarella

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General information 1. Registration Desk

The Registration Desk is available for information and distribution of badges and bags.

Upon arrival participants have to register at the Congress Secretariat in order to receive their materials including badges. Badges are needed to attend the congress scientific and social activities.

Participants should present their registration number to receive their materials 2. Congress App

The congress app is freely available. It helps you to set up your agenda, to contact poster authors and to access the scientific program, including speaker’s webpages.

3. Participation certificate

Official recognition of participation and poster presentation will be available in the “participant reserved area” up to ten days after the congress.

4. Badges

SBBq staff will provide badges for all delegates and accompanying persons. Access to scientific sessions and other activities, including social events, will be denied unless badges are used. Badges contribute greatly to promote personal contacts and also guarantee the full attention of the Congress Personnel, as well as security control. If you lose the badge, a duplicate will be provided at the Secretariat at cost of US$ 25,00.

5. Medical Service

There is an intensive-care unit and a Medical Service in the Foyer, with 1 doctor and 1 nurse available for emergency first aid. It will be available through the Congress during the following hours:

May14th (Tuesday) from 8:00 am to 20:30 pm

May15th (Wednesday), May16st (Thursday) , May17st (Friday) from 8:00 am to 7:30 pm

6. Information for speakers

The Multimedia Desk is located at the Speaker Room and is open during the following hours:

May14th (Tuesday) from 2:00 pm to 6:30 pm

May15th (Wednesday), May16st (Thursday) and May17st (Friday) from 8:00 am to 6:30 pm

7. Information for all participants

The SBBq Secretariat will be open during the following hours:

May14th (Tuesday) from 2:00 pm to 6:30 pm

May15th (Wednesday), May16st (Thursday) and May17st (Friday) from 8:00 am to 6:30 pm

8. Coffee with Exhibitors

The coffee break will be served on the ExpoSBBq space, with and extended time of 1 hour to give all participants the opportunity to interact with the exhibitors.

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15 Financial Support

We gratefully acknowledge our main sponsors

Gold Sponsor Financial Support also provide by

Silver Sponsor

Silver Sponsor

We also thank you for:

Referências

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