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Mutations of the Calcium Channel Gene cacophony Suppress Seizures in Drosophila.

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Table 1. Suppression of behavioral bang-sensitive paralytic phenotypes by cac TS2 and cacRNAi.
Fig 1. Drosophila cac TS2 electrophysiology. A. Electrical recording from a cac TS2 DLM fiber following delivery of 55 V HFS stimulation (0.5 msec stimuli at 200 Hz for 300 msec) at room temperature
Fig 2. Suppression of bang sensitive behavioral phenotypes by cac TS2 . A. Behavioral paralysis in sda hemizygotes (white bar) is suppressed in hemizygous double mutants cac TS2 /Y;;sda at room temperature (RT) by about a factor of 10 (black bar; n = 147)
Table 2. Seizure suppression of para bss1 by cac TS2 and other suppressors. The table lists four mutations that have been reported to revert para bss1 phe- phe-notypes in double mutant combinations
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