The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling.

(B) 293T cells were co-transfected with SuperTop reporter, pRL-CMV and b -catenin (S33Y) with or without the indicated TCF1 constructs, followed two days later by luciferase

Figure 2. Long-range Wnt-5A inhibits the ATF2-Luc reporter. A) For studying long-range signaling, Xwnt5A-EGFP transfected HEK293 cells seeded on thinCerts TC chambers were

transfected with vectors encoding CSL-firefly luciferase (Notch reporter) and TK-renilla luciferase (internal control reporter), together with NIC (Lane A) and increasing doses of

(B) HIF-1 a cooperated with Osx to inhibit Wnt pathway activity. HEK293 cells were transfected with a Topflash reporter along with 25 ng b - catenin without or with different groups

HEK293T cells were transfected with indicated expression plasmids of RIG-I wild type, mutations and ubiquitin, Novel E3/Stimulator of RIG-I... facilitated the ubiquitination of

TC620 cells were transfected with luciferase reporter plasmid for the early promoter, JCV E -LUC in the presence or absence of increasing amounts of Rad51 expression plasmid (0, 0.5

Reporter cells were cotransformed with a prey vector encoding SEC15 and a bait plasmid encoding either wild type or GTPase deficient mutant Sec4p Q79L with phosphorylated

To assess the involvement of RAR a and RXR a in the RA- dependent activation of Aldh1a2 promoter activity, we transfected COS-7 cells with RAR a and RXR a expression vectors and a