Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair.

In summary, these data indicate normal thymic T cell development in inducible Sgpl1-deficient mice, but retention of mature T cells in the thymus and LN, leading to reduced T

was impaired in the immunodeficient mice compared to immunocompetent Balb/c mice, as demonstrated by a significantly reduced bone content of the fracture callus in the late

Reduced trabecular thickness and BV/TV also were seen in male Akt2-deficient mice and their wild-type littermates compared with male wild-type mice from comparable Akt1-

P53-dependent apoptosis in miR-34 TKO/TKO cells and mice Having established that miR-34 is not required for cell cycle arrest in response to genotoxic stress in MEFs, we next sought

In conclusion, we found that MHCI proteins are expressed in the NAc of WT mice. We also found that LTP is enhanced whereas LTD is abolished in functional MHCI-deficient mice. We

Mice overexpressing BMP4 were previously shown to have decreased cell proliferation and stem/progenitor cell numbers in the dentate gyrus, whereas noggin transgenic mice have

In the elevated plus maze, the CD73 deficient mice travelled longer distances than the wt mice (p = 0.0057; Fig. 6A).The mice lacking CD73 demonstrated increased locomotor activity

Protective effects of Chlorella vulgaris (CV) on the percentage of primitive hematopoietic progenitor cells (c-Kit + Lin ) (A) and granulocytes/macrophages progenitor cells (Gr1 +