A field based 3D QSAR model of novel anti-microtubule agent noscapine and its derivatives

To better understand and explore the electrostatic and steric contributions to the binding of the discodermolide analogs, and to build predictive 3D QSAR models, CoMFA

However, the real predictive ability of the HQSAR model derived with the 207 training set molecules was assessed by predicting logBB values of an external test set of 48

To engender useful QSAR models and access the contributions of electrostatic and steric fields to the affinity of the data set inhibitors, CoMFA studies were performed upon the

O sistema de AIM, pode funcionar apenas a nível nacional, caso se pretenda que o medicamento seja aprovado apenas para colocação no mercado português – Procedimento

Um treinamento de força e de alta intensidade com este objetivo deve levar em consideração alguns fatores, como: o volume, que normalmente oscila entre 8-12 repetições

Model updating process is essentially an optimization problem that aims to update a set of parameters of a numerical model (usually, the natural frequencies and mode shapes) based

Leaf gas exchange parameters ((a) net photosynthesis—A n , (b) leaf transpiration— E, (c) stomatal conductance—gs) and (d) instantaneous water use efficiency (WUE: A n /E) variation