The E3 ubiquitin ligase activity of Trip12 is essential for mouse embryogenesis.

We have demonstrated here that TRIM21 is tyrosine phosphorylated only in this domain indicating a possible role for the tyrosine phosphorylation of TRIM21 regulating its ability to

Human Scribble (Vartul) Is Targeted for Ubiquitin- Mediated Degradation by the High-Risk Papillomavirus E6 Proteins and the E6AP Ubiquitin- Protein Ligase. A strategy for

MT and activity program on behavioral and depressive symptoms in PwD in a naturalistic setting. The MT integrated a program with other daily activities in a center for people

Recent- ly, GRAIL (the E3-ubiquitin ligase gene related to anergy in lymphocytes) was shown to be responsible for the Th2 hypore- sponsiveness in a mouse model of

Cells expressing Cul4b null allele in Cul4b heterozygous mice were selected against, to different degrees in different tissues, from early embryogenesis to early postnatal

To test whether the ligase activity of NleL is involved in pedestal formation, an EHEC strain expressing the chromosomal catalytically-dead mutant NleL C753A was used to infect

First described in Drosophila melanogaster , Seven in absentia (SINA) proteins are E3 ubiquitin ligases with a characteristic N-terminal RING (Really Interesting New

Cullin serves as a scaffold protein for the assembly of the multisubunit ubiquitin ligase complex that contains a RING domain protein at its C-terminus and a cullin-specific