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Olfactory dysfunction and neurotransmitter disturbance in olfactory bulb of transgenic mice expressing human A53T mutant α-synuclein.

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Academic year: 2017

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Fig 1. TH staining and locomotor activity. A (a, b, c): TH immunostaining in SN of wt (n = 4, a) and tg (n = 5, b) mice showed no significant difference at 10 m old
Fig 4. Odor habituation and discrimination on a non-social scent. A, B and C: As trials progressed, all mice spent gradually reduced time on contacting with a non-social odor
Fig 5. Odor memory test. Tg mice at 10 m old seem to spend slightly more time than age-matched wt mice at all intervals on an odor encountered before, but the statistical analysis showed no significant difference between tg (n = 16) and wt (n = 9) controls
Fig 7. Cholinergic denervation in OB of tg mice. A and B: ChAT + cells were decreased in mitral cell layer of OB in tg mice (n = 4) at 10 m old than wt littermates (n = 4)
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