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Molecular basis of live-attenuated influenza virus.

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Table 2. Mutation loci from Len-ca.
Figure 2. Mutations affect viral RNA synthesis at different temperatures. Viral RNAs in MDCK cells infected with the different viruses (16 10 4 pfu ) were analyzed by real-time PCR
Figure 5. Analysis of virus-specific CTL by tetramer-staining and Enzyme-linked immunospot (ELISPOT) for IFN-c
Figure 6. Protection against flu virus challenge in mice immunized by A/PR8 mutants. A

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