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Bmi1 is down-regulated in the aging brain and displays antioxidant and protective activities in neurons.

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Academic year: 2017

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Figure 1. Bmi1 is down-regulated in the aging mouse brain. A) Coronal sections from the cerebral cortex were analyzed by IHC using Bmi1 and NeuN (top panels), or Bmi1 and GFAP (lower panels) antibodies
Figure S1 Coronal sections of WT and Bmi1 2/2 mice brains were analyzed by IHC using Bmi1 (brown) andFigure 5
Figure S2 Cultured WT and Bmi1 2/2 neurons were infected or not with an adenovirus expressing a dominant-negative form of p53, and gene expression levels were analyzed by qPCR 48 hours later

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