Unusual natural killer cell responses to HIV-1 peptides are associated with protection against maternal-infant transmission of HIV-1

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HOST-PATHOGEN

INTERACTIONS

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CHRONIC

INFECTIONS

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Welcome to the 5th_{International Dominique Dormont Conference}

On behalf of the Organizing Committee, we are pleased to welcome you in Paris for the fifth Dominique Dormont International Conference.This annual conference is in memory of the spirit of Dominique Dormont and his dedication to research on pathogenesis and treatment of chronic infectious diseases.

The topic of this 5th _{event is " Mother-to-child transmitted viral diseases: from}

transmission to children care ".

It is devoted to cover mother-to-child transmission and pediatric viral infections, such as Human Cytomegalovirus, Hepatitis C Virus and Human Immunodeficiency Virus, and also other chronic infectious agents, close to Dominique Dormont's wide interest.The topics of the sessions selected by the organizing committee span from basic research to prevention and therapy. Attention is given to viral and host determinants of mother-to-child transmission, as well as means of prevention and control of transmission and disease in children, with drugs, immunotherapy and vaccine. Emphasis is also on the immunological development of host defences at the maternal-fetal interface and, in the newborn, basic concepts to understand pathogenesis and clinical outcome.The interaction between basic scientists and clinicians interested in different pathogens is intended to encourage the exchange of knowledge and foster new collaborations.

Each session is introduced by a keynote lecture by an expert in the field followed by abstract driven presentations. An effort has been made for encouraging presentations from young investigators.An international Scientific Committee has selected the abstracts for this programme giving priority to original unpublished studies to share exciting and recent results. The poster sessions are a further opportunity for stimulating exchanges between senior and young scientists and clinicians. Scholarships have been selected according to the quality of the abstracts and allocated to fellows from resource limited countries. To facilitate interdisciplinary discussions we have limited the attendance to a group of 200 participants.

We hope you will enjoy your stay in Paris.

Christine ROUZIOUX, Daniel BÉQUET and Stéphane BLANCHE

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O

RGANIZING

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OMMITTEE

Chair and Co-Chairs

C. Rouzioux D. Béquet S. Blanche

Core Local Organizing committee

F. Barré-Sinoussi P. Clayette H. Fleury G. Gras J. Grassi G. Inchauspé R. Le Grand E. Menu N. Tordo M. Wainberg

Extended Local Organizing committee

B. Bazin F.X. Blanc G. Carcelain G. Chaouat F. Dabis C. Davrinche C. Delacourt A. Faye P. Msellatti L. Quintana-Murci G. Scarlatti D. Scott J.M. Tréluyer P. Van de Perre

I

NTERNATIONAL

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CIENTIFIC

P

ROGRAMME

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OMMITTEE

E. Abrams(USA)

G. Biberfeld(SE)

H. Coovadia(ZA)

M. Cotton(ZA)

C. Courpotin(F)

D. Ekouevi(CI)

R. Ekpini(USA)

C. Giaquinto(I)

G. Gray(ZA)

G. John-Stewart(USA)

C. Katlama(F)

M. Lallemant(TH)

P. Lepage(B)

M. Marthas(USA)

N. Meda(BF)

P. Miotti(USA)

L. Mofenson(USA)

M. Morgado(BR)

M.L. Newell(ZA)

P. Rossi(USA)

F. Rouet(F)

R. Ruprecht(USA)

B. Spire(F)

M. Tejiokem(CM)

P. Vaz(MZ)

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The Organizing Committee wishes to extend its thanks and appreciation to :

■ The following sponsors for their contributions:

• ANRS

101, rue de Tolbiac 75013 Paris www.anrs.fr

• Bio-Rad

3, boulevard Raymond Poincaré 92430 Marnes la Coquette www.bio-rad.com

• CEA - Commissariat à l’Énergie Atomique

Direction des Sciences du Vivant 91191 Gif sur Yvette Cedex www.cea.fr

• Cytheris

175, rue Jean-Jacques Rousseau 92130 Issy Les Moulineaux www.cytheris.com

• Fondation Mérieux

17, rue Bourgelat 69002 Lyon

www.fondation-merieux.org

• GlaxoSmithKline

100, route de Versailles 78163 Marly-le-Roi cedex www.gsk.com

• National Institute of Health

Office of AIDS Research 5635 Fishers Lane, suite 4000, room 4016 D Bethesda, MD20892, USA www.nih.gov

BIO-RAD

A

CKNOWLEDGEMENTS

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• Roche Diagnostics

Division Lab Network

2, avenue du Vercors - 38240 Meylan www.rochediagnostics.fr

• Sanofi Aventis Groupe

82, avenue Raspail 94255 Gentilly Cedex www.sanofi-aventis.com

• Sidaction

228, rue du Faubourg Saint-Martin 75010 Paris

www.sidaction.org

• Spi-Bio

CEA - 18, route du Panorama - BP6 92265 Fontenay aux Roses cedex www.spibio.com

• Tibotec, Division Janssen-Cilag

1, rue Camille Desmoulins

92787 Issy les Moulineaux Cedex 9 www.tibotec-vih.fr

• World Health Organization

www.who.int

■ Mrs Elisabetta FARINAfor the illustration of the conference.

■ Association Dominique Dormont

■ Conseil Régional d’Île-de-France

■ Université de Strasbourg

■ The World Health Organization,Department of Reproductive Health and Research, "Art for Health" project, for providing the painting exhibition.

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T

HURSDAY

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17:00

Opening Ceremony

Chairs: F. Barré-Sinoussi, J-F. Delfraissy

Welcome addresses

J.E. Touzet,Directeur de l’Ecole d’Application des Armées du Val de Grâce

C. Rouzioux , S. Blanche, D. Béquet,chairs of the conference

Introductory lecture L1 17:15 Human genome variability and host-pathogen interactions

L. Quintana-Murci

Session 1

Mechanisms of viral transmission and physiopathology in

infected infants

Chairs: E. Menu, G. Scarlatti

Keynote Lecture L2 17:45 Perspectives on pathogenesis and prevention of congenital herpes

virus infection

M. Schleiss

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Oral presentations

18:15 Effects of HPV-16 early proteins on trophoblastic cells

S. Boulenouar, C. Weyn, M. Van Noppen, M. Ali Mohamed, F. Bex,

A. Noël, Y. Englert, V. Fontaine O1

18:30 Activation of PPARgg by human CMV for de novo replication

impairs invasiveness of cytotrophoblast from early placenta

B.Rauwel, B.Mariamé, H.Martin, D. Evain-Brion, T. Fournier,

C. Davrinche O2

18:45 Mother-to-child transmission of HTLV-1: in vitro study of HTLV-1 passage across a tight human epithelial barrier

S. Martin-Latil, N. Gnädig, A. Mallet, M.C. Prevost, M. Desdouits,

A. Gessain, S. Ozden, P.E. Ceccaldi O3

19:00 Dendritic cells sample HIV-1 through an intestinal epithelial cell monolayer

M. Cavarelli, C. Foglieni, M. Rescigno, G. Scarlatti O4

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Session 2

Mother & child immunity and transmission

Chairs: M. Morgado, D. Scott-Algara

Keynote Lecture L3 9:00 Mother and fetal immunity to CMV

A. Marchant

9:30 Unusual natural killer cell responses to HIV-1 peptides are associated with protection against maternal-infant transmission of HIV-1 C. Tiemessen, S. Shalekoff, S. Meddows-Taylor, D. Schramm,

M. Papathanasopoulos, G. Gray, G. Sherman, A. Coovadia, L. Kuhn O5

9:45 CD14+_{cells are the main targets for HIV-1 infection in first trimester}

pregnancy human uterine mucosa

R. Marlin, M.T. Nugeyre, C. de Truchis, N. Berkane, A. Gervaise,

F. Barré-Sinoussi, E. Menu O6

10:00 Phenotypic characterization of HIV-specific CD8 T cells during acute infant HIV infection

J. Slyker, T. Dong, G. John-Stewart, B. Lohman-Payne, M. Reilly, A. Atzberger, S. Taylor, E. Maleche-Obimbo, D. Mbori-Ngacha,

S. Rowland-Jones O7

10:15 Human immunodeficiency virus-specific B cells in human breast milk E. Tuaillon, D. Valea, Y. Al Tabaa, P. Becquart, N. Meda, K. Bollore,

J.P. Vendrell, P. Van de Perre O8

10:30 Transmission of hepatitis B virus (HBV) minor variants in children born to HBV/HIV co-infected mothers

W. Khamduang, C. Gaudy-Graffin, A. Moreau, N. Ngo-Giang-Huong, G. Jourdain, M. Lallemant, S. Pipatnakulchai, C. Putiyanun,

S. Kunkongkapan, P. Wannarit, S. Sirinontakan, W. Ardong,

W. Sirirungsi, A. Goudeau O9

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10:45 Coffee break and poster viewing

Session 3

Treatment and prevention in mother and child

Chairs: T. Sint, P. Van de Perre

Keynote Lecture L4 11:15 The art and science of preventing and treating HIV disease in

children: a life cycle approach

E. Abrams

11:45 Very Early diagnosis of HIV infection in newborn at day 0-day 3 on DBS in Cambodia

S. Ngin, S. Kruy Leang, C. Kong, S. Im, V. Lim, M. Ly Ek, D. Augustinova, K. Koum, C. Rouzioux, E. Nerrienet O10

12:00 High frequency of belated HIV diagnoses in pediatric population in Buenos Aires, Argentina

M. Vignoles, G. Barboni, M.R. Agosti, M. García, S. González Ayala,

H. Salomón O11

12:15 New approch for congenital CMV infection diagnosis in neonates: sensibility and specificity of CMV detection in dried blood spots M. Leruez-Ville, C. Vauloup-Fellous, S. Couderc, S. Parat, S. Oucherif,

J.F. Magny O12

12:30 Use of chloroquine in reducing mother to child transmission of HIV-1 during breastfeeding

M. Naarding, S. Luchters, J. Vyankandondera, F. Wit, N. Veldhuijzen, B. Kankindi, R. Sparidans, J. Beijnen, G. Pollakis, J. Boelaert, J. Lange,

W. Paxton O13

12:45 High emergence of drug resistance after HAART interruption at delivery in a cohort of HIV+ pregnant women submitted to antiretroviral treatment to prevent mother-to-child transmission in Rio de Janeiro, Brazil

J.H. Pilotto, B. Grinsztejn, V. Veloso, J.C. Couto-Fernandez, A. Rodrigues-Pedro, C.A. Velasco-de-Castro, J. Eurico Ribeiro,

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13:00 Risk factors for HCV infection in HIV positive pregnant women and rate of HCV perinatal transmission in Thailand

N. Ngo-Giang-Huong, L. Decker, W. Sirirungsi, S. Le Coeur, G. Jourdain, W. Khamduang, S. Kanjanavanit, W. Matanasaravoot, C. Putiyanun, F. Barin, M. Lallemant O15

13:15 Lunch and poster viewing

Special Lecture L5

Chair: S. Blanche

14:15 Pharmacology of antiretroviral drugs in the pregnant woman: the point of view of the clinician

L. Mandelbrot

Debate

14:45 Prevention of breast-feeding transmission of HIV-1: treating the mother, the baby, or both of them?

Chair: M.L. Newell

Prevention of breastfeeding transmission of HIV-1 by infant peri-exposure prophylaxis

P. Van de Perre L6 Universal antiretroviral therapy for pregnant and breastfeeding HIV-infected women: Towards the elimination of mother-to-child transmission of HIV-1 in resource-limited settings?

R. Becquet L7

Session 4

MTCT prevention programme implementation and evaluation

Chairs: D. Ekouevi, V. Noba

Keynote Lecture L8 16.00 Challenges in the management of HIV infected pregnant

women and their infants: progress in PMTCT programmes

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16:30 Barriers to HIV testing among mothers at a maternity ward in Phnom Penh, Cambodia

K. Kanal, Y. Sasaki, K. Kakimoto, V. Sathiarany, Y. Shirayama, M. Ali, C. Kuroiwa, K. Shibuya O16

16:45 PMTCT activities implementation : case of côte d'ivoire, from ACONDA's experience

H.P. Aka Kouamé, N. Dakoury Dogbo, T. Siaka, V. Noba O17

17:00 Effectiveness of a district-wide programme for the prevention of mother–to-child transmission of HIV in Cambodia. Experience from six maternity units in Phnom Penh and Kandal

D. Augustinova, A. Stranska, K. Koum, S. Ean, S. Vong, C. Kong,

S. Ngin, E. Nerrienet, M. Bandzak O19

17:15 Is marital status and information of the father associated with access to prevention of mother-to-child HIV transmission? C. Jasseron, L. Mandelbrot, S. Blanche, R. Tubiana, J. Le Chenadec,

J.P. Teglas, C. Dollfus, A. Faye, C. Rouzioux, J. Warszawski O20

17:30 Why do HIV negative mothers refuse to participate in a clinical research involving HIV positive mothers in Cameroon?

M.C. Tejiokem, G. Guemkam, C. Same Ekobo, I. Penda, A. Nga, P. Mbida, Marie L. Belinga, C. Tocko, F. Ateba Ndongo, J. Audrey Ndongo, M. Mekoudjou, A. Kfutwah, D. Rousset,

J. Warszawski, A. Faye O21

18:15

Concert at the Val de Grâce Chapel

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Session 5

Infected child treatment and coinfections

Chairs: K.T.K. Dung, E. Nerrienet

Keynote Lecture L9 9.00 TB exposure and disease in children born to HIV-infected

mothers

B.J. Marais

9:30 High incidence of invasive group B streptococcal infections in uninfected infants born to HIV-1-infected mothers

C. Epalza, T. Goetghebuer, M. Hainaut, P. Barlow, A. Dediste, P. Melin,

J. Levy O22

9:45 Perinatal transmission of cytomegalovirus (CMV) in children born to HIV positive and negative women in Cameroon

A. Kfutwah, M. Tejiokem, A. Faye, M. Yonga, J. Warszawski, S. Blanche, C. Rekacewicz, F. Ateba, J. Ndongo, G. Guemkam, C. Same-Ekobo,

C. Rouzioux, M. Leruez-Ville, P. Boisier, D. Rousset O23

10:00 Frequency of resistant virus and options for a second-line treatment for HIV-1 infected children under HAART in Mozambique

M.L. Chaix, I. Jani, E. Macassa, D. Bila, A. Vubil, S. Andersson,

C Rouzioux, P Vaz, S. Blanche O24

10:15 Lopinavir/ritonavir-based second line antiretroviral treatment in children at the National Pediatric Hospital, Phnom Penh, Cambodia S. Sam, V. Ung, C. Huot, B. Chan, K. Yuvatha, C. Courpotin, G. Adam, S. Ngin, E. Nerrienet, Y. Meng Chhour O25

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11:00

Closing ceremony

Chairs: D. Béquet, S. Blanche, C. Rouzioux

Concluding remarks C. Rouzioux

Memorial lecture L10

Viruses and the developing nervous system

M. Tardieu

Welcome to the DDIC 2010 M. Tardieu

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P

OSTERS

P1 The trophoblat : a model to study HPV transcription, replication and host cell interactions

V. Fontaine, S. Boulenouar, C. Weyn, Y. Englert

P2 Evolution of HIV-1 envelope sequences and coreceptor tropism during pregnancy

D. Ransy, J. Couto, B. Akouamba, J. Samson, N. Lapointe, M. Boucher, H. Soudeyns

P5 Maternal neutralizing antibodies against a CRF01_AE primary isolate are associated with a low rate of intrapartum HIV-1 transmission in Thailand S. Thenin, T. Samleerat, G. Jourdain, N. Ngo-Giang-Huong, A. Moreau, P. Leechanachai, M. Lallemand, F. Barin, M. Braibant

P6 HCV infection in a sample of pregnant women in central Poland: seroprevalence and risk factors

M. Aniszewska, B. Kowalik-Mikolajewska, M. Pokorska-Lis, M. Kalinowska

P7 CD4+_{T lymphocyte response to primary CMV infection}

P. Antoine, V. Olislagers, S. Lecomte, C. Liesnard, C. Donner, A. Marchant

P10 Early diagnosis of HIV-1 infection in infants using RNA quantitative PCR in Burkina Faso

H. Somlare, L. Sangare, S. Yameogo, C. Ouedraogo, Y. Dembele, M. Soro, P. Some, C. Yonaba

P11 Couple issues in the last pregnancy experience of HIV+_{women knowing}

their status before pregnancy

N. Trocmé, M.D. Tabone, M.F. Courcoux, L. Stengel, C. Dollfus

P12 Evolution of the biological follow-up of efficiency and tolerance of a once daily antiretroviral treatment with 3TC+DDI+EFV in children infected with HIV-1 (clinical trial ANRS 12 103)

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P13 Transient elastography (fibroscan) in HIV-1 vertically infected children. A cross-sectional study

F. Monpoux, E. Huguon, R. Truchi, A. Rubio, V. Triolo, A. Deville, P. Boutte, A. Tran

P14 Motherhood in HIV+_{women infected in early childhood}

C. Dollfus, N. Trocmé, M.D. Tabone, G. Vaudre, C. Courpotin, G. Leverger

P15 Health care of children diagnosed HIV positive before 18 months in the Chea Chumneas Hospital, Takhmao, Cambodia

D. Augustinova, B. Ban, C. Kong, K.S. La, S. Prem Prey, M. Kong, S. Ngin, E. Nerrienet, M. Bandzak

P16 A Ukraine birth cohort of children with vertically acquired HIV infection S. Mahdavi, C. Thorne, R. Malyuta, I. Semenenko, T. Pilipenko

P17 Adherence in HIV-1 infected children taking once daily HAART with Didanosine + Lamivudine + Efavirenz in West Africa (ANRS 12103 clinical trial)

J. Somé, B. Nacro, H. Hien, H. Tamboura, E. Zouré, S. Diagbouga, A. Ouiminga, A. Drabo, A. Hien, S. Yaméogo, P. Van De Perre, P. Msellati

P18 Vertical transmission of hepatitis C virus in children born to HIV/HCV coinfected mothers in Poland

S. Dobosz, M. Marczynska, A. Oldakowska, M. Szczepanska-Putz, K. Zawadka

P19 Are recommended dose of Efavirenz optimal in young children? (ANRS 12103)

D. Hirt, S. Urien, M. Olivier, H. Peyrière, B. Nacro, S. Diagbouga, E. Zouré, F. Rouet, H. Hien, P. Msellati, P. Van de Perre, J.M. Tréluyer

P20 Didanosine population pharmacokinetics in West African HIV-infected children administered once daily tablets in relation to efficacy after one year of treatment (ANRS 12103)

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I

NDEX

A

Abrams E. L4 Adam G. O25 Agosti M.R. O11 Aka Kouame H.P. O17 Akouamba B. P2 Al Tabaa Y. O8 Ali M. O16 Ali Mohamed M. O1 Andersson S. O24 Aniszewska M. P6 Antoine P. P7 Ardong W. O9 Ateba F. O21, O23 Atzberger A. O7

Augustinova D. O10, O19, P15

B

Ban B. P15 Bandzak M. O19, P15 Barboni G. O11 Bardin C. P20 Barin F. O15, P5 Barlow P. O22 Barré-Sinoussi F. O6 Becquart P. O8 Becquet R. L7 Beijnen J. O13 Belinga L. O21 Berkane N. O6 Bex F. O1 Bila D. O24

Blanche S. O20, O23, O24 Boelaert J. O13

Boisier P. O23 Bollore K. O8 Boucher M P2 Boulenouar S. O1, P1 Boutte P. P13 Braibant M. P5

C

Cavarelli M. O4 Ceccaldi P.E. O3 Chaix M.L. O24 Chan B O25 Coovadia A. O5 Couderc S. O12 Courcoux M.F. P11 Courpotin C. O25, P14 Courrier J. O14 Couto J. P2 Couto-Fernandez J.C. O14

D

Dakoury Dogbo N. O17 Davrinche C. O2 De Truchis C. O6 Decker L. O15 Dediste A. O22 Dembele Y. P10 Desdouits M. O3 Deville A. P13

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Dobosz S. P18 Dollfus C. O20, P11, P14 Dong T. O7

Donner C. P7 Drabo A. P12, P17

E

Ean S. O19 Englert Y. O1, P1 Epalza C. O22 Eurico Ribeiro J. O14 Evain-Brion D. O2

F

Faye A. O20, O21, O23 Foglieni C. O4

Fontaine V. O1, P1 Foulongne V. P20 Fournier T. O2

G

Garcia M. O11 Gaudy-Graffin C. O9 Gervaise A. O6 Gessain A. O3 Gnadig N. O3 Goetghebuer T. O22 Gonzalez Ayala S. O11 Goudeau A. O9 Gray G. O5 Grinsztejn B. O14 Guemkam G. O21, O23

H

Hainaut M. O22 Hien A. P12, P17 Hien H. P12, P17, P19, P20 Hirt D. P19, P20 Huguon E. P13 Huot C. O25

I

Im S. O10 Ismerio R. O14

J

Jani I. O24 Jasseron C. O20 John-Stewart G. O7 Jourdain G. O9, O15, P5

K

Kakimoto K. O16 Kalinowska M. P6 Kanal K. O16 Kania D. P12 Kanjanavanit S. O15 Kankindi B. O13 Kfutwah A. O21, O23 Khalili R. O14 Khamduang W. O9, O15 Kong C. O10, O19 Kong M. P15

Koum K. O10, O19, P15 Kowalik-Mikolajewska B. P6

Kruy Leang S. O10 Kuhn L. O5 Kunkongkapan S. O9 Kuroiwa C. O16

L

La K.S. P15 Lallemant M. O9, O15, P5 Lange J. O13 Lapointe N. P2 Le Chenadec J. O20 Le Cœur S. O15 Lecomte S. P7 Leechanachai P. P5 Leruez-Ville M. O12, O23 Leverger G. P14 Levy J. O22 Liesnard C. P7 Lim V. O10 Lohman-Payne B. O7 Luchters S. O13 Ly Ek M. O10

M

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Marczynska M. P18 Mariame B. O2 Marlin R. O6 Martin H. O2 Martin-Latil S. O3 Matanasaravoot W. O15 Mbida P. O21 Mbori-Ngacha D. O7 Meda N. O8 Meddows-Taylor S. O5 Mekoudjou M. O21 Melin P. O22 Meng-Chhour Y. O25 Menu E. O6 Monpoux F. P13 Moreau A. O9 P5 Morgado M.G. O14

Msellati P. P12, P17, P19, P20 Muri S. O14

N

Naarding M. O13

Nacro B. P12, P17, P19, P20 Ndongo J.A. O21, O23 Ndongo F.A. O21, O23 Nerrienet E. O10, O19, O25, P15 Newell M.L. L8

Nga A. O21

Ngin S. O10, O19, O25, P15 Ngo-Giang-Huong N. O9, O15, P5 Noba V. O17 Noel A. O1 Nugeyre M.T. O6

O

Oldakowska A. P18 Olislagers V. P7 Olivier M. P19 Oucherif S. O12 Ouedraogo C. P10 Ouiminga A. P12, P17, P20 Ozden S. O3

P

Papathanasopoulos M. O5 Parat S. O12 Paxton W. O13 Penda I. O21

Peyriere H. P19 Pilipenko T. P16 Pilotto J.H. O14 Pipatnakulchai S. O9 Pokorska-Lis M. P6 Pollakis G. O13 Prem Prey S. P15 Prevost M.C. O3 Putiyanun C. O9, O15

Q

Quintana-Murci L. L1

R

Ransy D. P2 Rauwel B. O2 Reilly M. O7 Rekacewicz C. O23 Rescigno M. O4 Rodrigues-Pedro A. O14 Rouet F. P12, P19, P20 Rousset D. O21, O23 Rouzioux C. O10, O20, O23, O24 Rowland-Jones S. O7

Rubio A. P13

S

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Some J. P17 Somlare H. P10 Soro M. P10 Soudeyns H. P2 Sparidans R. O13 Stengel L. P11 Stranska A. O19 Szczepanska-Putz M. P18

T

Tabone M.D. P11, P14 Tamboura H. P17 Tardieu M. L10 Taylor S. O7 Teglas J.P. O20 Tejiokem M.C. O21, O23 Thenin S. P5 Thorne C. P16 Tiemessen C. O5 Tocko C. O21 Tran A. P13 Treluyer J.M. P19, P20 Triolo V. P13 Trocme N. P11, P14 Truchi R. P13 Tuaillon E. O8 Tubiana R. O20

U

Ung V. O25 Urien S. P19, P20

V

Valea D. O8

Van De Perre P. L6, O8, P12, P17 P19, P20 Van Noppen M. O1 Vaudre G. P14 Vauloup-Fellous C. O12 Vaz P. O24 Velasco-De-Castro C.A. O14 Veldhuijzen N. O13 Veloso V. O14 Vendrell J.P. O8 Vignoles M. O11 Vong S. O19 Vubil A. O24 Vyankandondera J. O13

W

Wannarit P. O9

Warszawski J. O20, O21, O23 Weyn C. O1, P1 Wit F. O13

Y

Yameogo S. P10, P12, P17 Yonaba C. P10 Yonga M. O23 Yuvatha K. O25

Z

Zamadka K. P18

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C

ONGRESS

O

FFICE

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