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ESCRT-0 is not required for ectopic Notch activation and tumor suppression in Drosophila.

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Academic year: 2017

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Figure 1. Hrs , Stam or Hrs , Stam double mutant tissue do not display altered tissue architecture
Figure 2. ESCRT-0 mutations lead to accumulation of ubiquitylated cargoes, as well as of Notch and Dome in endosomes
Figure 3. ESCRT-0 mutants do not affect endosomal maturation. (A) Example of eye tissue almost completely homozygous for a WT (left) or mutant chromosome (right)
Figure 4. ESCRT-0 mutations do not alter Notch signaling in FE cells. (A–F) Mosaic egg chambers at stages 5–7 of oogenesis stained to detect the Notch targets Hnt (A–C) and Cut (D–F) and f-Actin

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