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The interface between methyltransferase and polymerase of NS5 is essential for flavivirus replication.

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Academic year: 2017

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Figure 1. Hydrophobic network and GTR sequence of JEV NS5 are highly conserved in the Flavivirus genus
Figure 3. Functional analysis of NS5 GTR sequence mutations in JEV infectious cDNA clone
Figure 4. Functional analysis of NS5 interface and GTR sequence mutations in a DENV-2 infectious cDNA clone

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