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Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein.

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Academic year: 2017

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Figure 1. DAS181 inhibits pandemic IFV A(H1N1): Immunofluorescent detection of 2009 A(H1N1) foci in MDCK cells
Table 2. DAS181 inhibits pandemic IFV A(H1N1): Viral Yield in MDCK culture (log10 infectious particles per 100 m l).
Figure 3. DAS181 inhibits pandemic IFV A(H1N1) viral replication in ex vivo human bronchi tissue
Figure 5. DAS181 inhibits pandemic IFV A(H1N1)-induced body weight loss in mice. BALB/c mice were inoculated with the pandemic influenza A(H1N1) virus A/Mexico/4108/2009 (1000 MID 50 / mouse, i.n.)

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