Skeletal muscle-specific ablation of gamma(cyto)-actin does not exacerbate the mdx phenotype.

Analysis of the predicted aa se- quences revealed two distinct types of cytoplasmic actins, one cardiac muscle actin type and one skeletal muscle actin type that were expressed

induced in both human DMD and mouse models of muscular dystrophy, we attempted to model this increase by creating skeletal muscle-specific transgenic mice with increased

Because dystrophin binds actin in vitro (R ybakova et al., 1996) and the costameric cytoskeleton is altered in dystro- phin-deficient muscle (Minetti et al., 1992, 1994; Porter et

PCP led to up-accumulation of a protein spot containing the cytoskeleton protein species gamma actin (spot 889). Several roles have been attributed to actin network,

Activation of phosphofructokinase induced by F- actin: Since PFK activity seems to increase on an actin-enriched fraction by insulin stimulation, we decided to investigate the

More recently, the presence of actin isoforms, restricted to different skeletal muscle types (white and red muscle), were also characterized in other fish species, such as

Together with FSP1, a -smooth muscle actin ( a sm actin) and CD45, cadherin-9 is a novel cell surface marker, which can be used to differentiate the depicted renal

Skeletal and cardiac muscle fibrosis were also significantly increased in untreated mdx mice compared to wild type, but there was no significant improvement in treated mdx mice..