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Genetic Evidence for Elevated Pathogenicity of Mitochondrial DNA Heteroplasmy in Autism Spectrum Disorder.

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Fig 1. Characteristics of mtDNA variants. (A) The nonsynonymous-synonymous rate ratio (hN/hS) for all possible nucleotide substitutions, observed heteroplasmies, and homoplasmies on mtDNA
Fig 2. Comparison of mtDNA mutation burden and pathogenicity between autistic probands and non- non-autistic siblings
Table 1. Contribution of private mtDNA mutations to ASD.
Table 2. Contribution of private mtDNA mutations to ID in ASD.
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