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The Expression of Bone Morphogenetic Protein 2 and Matrix Metalloproteinase 2 through Retinoic Acid Receptor Beta Induced by All-Trans Retinoic Acid in Cultured ARPE-19 Cells.

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Academic year: 2017

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Table 1. Primer sequences used in RT-PCR.
Fig 1. The Effect of ATRA on survival in ARPE-19 cells. ATRA caused a low level of apoptosis (<10%) at concentrations from 10 −9 to 10 −6 mol/l, but the cell morphology remained normal
Fig 2. RARs and RXRs expressions in ARPE-19 cells. RARs mRNA was strongly expressed in ARPE-19 cells, whereas RXRs expression was not detected (Fig 2A and 2B)
Fig 3. Time-related changes in expression of RARβ mRNA and protein. A significant increase in the RARβ band intensity was detected for both mRNA (Fig 3A and 3B) and protein (Fig 3A and 3C) at 24 h and 48 h after treatment with 10 −6 mol/l ATRA (P<0.05).
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