Synergistic Effect of Subtoxic-dose Cisplatin and TRAIL to Mediate Apoptosis by Down-regulating Decoy Receptor 2 and Up-regulating Caspase-8, Caspase-9 and Bax Expression on NCI-H460 and A549 Cells

The in vitro results showed that nicotine up-regulated the expression of α 5-nAChR protein and inhibited cis- platin-induced apoptosis by regulating α 5-nAChR/AKT signaling pathway

In the present study, we examined the effects of curcumin on the proliferation of human colon adenocarcinoma HT-29 cells by the

Our results revealed that ziyuglycoside II could inhibit the proliferation of BGC-823 cells by inducing apoptosis but not cell cycle arrest, which was associated with regulation

ECPS exhibited antimelanogenic activity by down-regulating the expression of tyrosinase, MITF, and TRP-1 without cytotoxic effects in B16F10 melanoma cells.. In conclusion, ECPS

The effects of gefitinib and erlotinib on (A) mRNA and (B) protein expression levels of unfolded protein response (UPR)-related genes in A549 cells were investigated.. Each

crucial constitutive (and early) role in ifn b expression followed by an equally impor- tant and potentially more general later role in regulating expression of genes involved

Where Control, group of animals treated with vehicle (2% gum acacia suspension, orally) daily for 15 consecutive days; Cisplatin, group of animals treated with 2% gum acacia

BP-C1 , is significantly reduced cell viability of human breast cancer cells through induction of apoptosis via activation of caspase 8 and caspase 9, increasing the expression