Inhibition of methyltransferases accelerates degradation of cFLIP and sensitizes B-cell lymphoma cells to TRAIL-induced apoptosis.

To determine whether CAERS inhibited the cell growth of A549 cells by inducing apoptosis and whether CAERS-induced apoptosis accounts for its ability to enhance CDDP-induced

Silencing of FANCF in breast cancer cell lines led to significantly increased DNA damage compared with the cells treated with control shRNA (Figure 3).. Silencing of FANCF induced

Histopathological testing of the tumor confirms the diagnosis of lymphoma and immunophenotyping differentiates primary nasal lymphoma - derived from T-cells - from B-cell

Effects of polydatin on cell apoptosis in liver cancer cell lines treated with different concentrations of polydatin for 48 h (A), determined by fl ow cytometry assay; B, effect of

Using cholangiocarcinoma cells as a model of TRAIL resistance, we found that Hedgehog signaling blockade sensitized these cancer cells to TRAIL cytotoxicity independent of

Because we found that the combined treatment with casticin and TRAIL strongly induced cytotoxicity in gastric cancer cells, we next examined the effect of the treatment on

Diffuse large B-cell lymphoma (DLBCL) is a non- Hodgkin lymphoma (NHL) subtype characterized by diffuse proliferation of large neoplastic B lymphoid cells with nuclear

follicular lymphoma; 15 patients with diffuse large B-cell lymphoma; 7 patients with small lymphocytic B-cell lymphoma/chronic lymphocytic leukemia; 3 patients with mantle cell