• Nenhum resultado encontrado

FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF CYCLODEXTRIN INCLUSION COMPLEXED WATER INSOLUBLE DRUG: GLIMIPIRIDE

N/A
N/A
Protected

Academic year: 2017

Share "FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF CYCLODEXTRIN INCLUSION COMPLEXED WATER INSOLUBLE DRUG: GLIMIPIRIDE"

Copied!
6
0
0

Texto

Loading

Imagem

Table 2: Phase Solubility Studies of Glimepiride: β- Cyclodextrin Complexes and Glimepiride: HP-β-Cyclodextrin Complexes  Concentration of β-CD (mM)  Concentration of GMP (mM)  Concentration of HP-β-CD  (mM)  Concentration of GMP (mM)
Table 3: Drug Content Estimation of Glimepiride in the β-CD and HP-β-CD Inclusion Complexes  Formulation Code  Percent Drug Content ±SD

Referências

Documentos relacionados

This work aimed to verify the interferences caused by the use of excipients for immediate release tablets based on benznidazole obtained by direct compression and the accomplishment

Different mass transport processes may occur during the drug release from the polymer-based matrix tablets, including water imbibition into the system, polymer

The susceptibility of the matrix tablets to the enzymatic action of colonic bacteria was assessed by continuing the drug release studies in simulated colonic luids prepared using

ranitidine tablets of a reference drug (product A) and a generic (product B) and a similar (product C) drug marketed in Bahia, Brazil using a simple, fast and inexpensive

Taking all of this into account, the aim of the present study was to prepare tablets by direct compression of sodium alendronate-loaded Eudragit ® S100 microparticles using

Tablets containing diferent concentrations of Carbopol (CP), hydroxypropyl methylcellulose (HPMC), or ethyl cellulose (EC) were prepared using direct compression and the drug

The prepared tablets were evaluated for hardness, friability, disintegration time and in vitro drug release.. Furthermore, the interaction of clopidogrel with the

Water solubility and drug dissolution rates were signiicantly increased after the formation of inclusion complexes with the cyclodextrins evaluated in relation to the physical