Reactive oxygen species, apoptosis and cancer

In type I cells, death receptors (e.g. Fas) induce strong caspase-8 activation, which alone is suffi cient to lead to robust proces- sing of effector caspases such as caspase-3

Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mecha- nism requiring cell contact and mediated by both the cell- associated form of TNF and

Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry.. Novel approach for simultaneous evaluation of cell phenotype,

To determine whether CAERS inhibited the cell growth of A549 cells by inducing apoptosis and whether CAERS-induced apoptosis accounts for its ability to enhance CDDP-induced

The present study shows that TNF inhibits the histone H1 and pRb kinase activities associated with CDKs in the cell lines WEHI, L929 and HeLa undergoing cell cycle arrest and

The aim of the present study was to determine the effect of the combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and adriamycin (ADM) on the human

vexillum venom by inducing oxidative stress mediated mechanisms in tumor cells and suggest that the venom contains novel molecules with potential anticancer activity.. Keywords:

Annexin V-FITC, caspase-3, Angiotensin Converting Enzyme activity and Tumor Necrosis Factor alpha (TNF- α ) assays were performed to evaluate apoptosis and inflammatory events..