• Nenhum resultado encontrado

MDRL lncRNA regulates the processing of miR-484 primary transcript by targeting miR-361.

N/A
N/A
Protected

Academic year: 2017

Share "MDRL lncRNA regulates the processing of miR-484 primary transcript by targeting miR-361."

Copied!
12
0
0

Texto

Loading

Imagem

Figure 1. miR-361 in the nucleus is able to regulate mature miR-484 levels. A. Microarray results depicting the log-log scatter plot of intensity of miRNA expression in nuclei from control versus A/R treatment
Figure 2. miR-361 can directly bind to pri-miR-484 and prevents its processing by Drosha into pre-miR-484
Figure 4. MDRL can regulate miR-361 expression and activity. A. LncRNAs expression levels upon treatment with A/R
Figure 5. Interaction between MDRL and miR-361. A. MDRL RNA contains a site complementary to miR-361
+2

Referências

Documentos relacionados

The serum levels of miR-3200, miR-21, and miR-205 at any point during chemotherapy treatment were not predictive for DFS; however, high levels of miR-451 at the time of diagnosis

Reads that originate from the mouse pre-miR-290 and the human pre-miR-371 (the most upstream hairpins in the clusters) map predominantly to the 5 9 - strand of the hairpin

Also, we confirmed that the expression of three members of the miR-35- 41 family (miR-35-3p, miR-36-3p, and miR-39-3p) was upregulated in 12-hr starved worms, consistent with

FINDINGS We found several cellular miRNAs that target a conserved region within the 3′ untranslated region (3′ UTR) of the genome of the four DENV serotypes and found

We similarly demonstrated that miR-424 combined with miR-381 could augment the apoptosis of 786-O cells and directly affect cell cycle progression by targeting WEE1.. Thus, miR-424

The present study aimed to explore the potential roles of circulating miR-149, miR-424 and miR-765 as non-invasive biomarkers for the diagnosis of coronary artery disease in

O aumento na transcrição e consequente fosforilação de AMPKαβ, isoforma predominante no músculo esquelético, ativa processos catabólicos tais como a captação de glicose

The inclusion of patients with benign breast tumors enabled the observation that miR-148b, miR-652 and miR-801 levels are even elevated in the plasma of women with benign tumors