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A hepatitis C virus infection model with time-varying drug effectiveness: solution and analysis.

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Academic year: 2017

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Figure 1. Example of a biphasic decline of HCV, following a short delay, after initiation of interferon-a therapy at t~0
Figure 2. HCV viral load undergoes biphasic decay upon initiation of silibinin treatment at time t~0
Table 1. Model parameter estimates obtained for different drug treatments of chronic HCV.
Fig. 4 shows the terms A, B, C, and D plotted against time for sibilinin parameters (nw1; see Table 1), compared to the exact solution (11)
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