Mining SNPs in extracellular vesicular transcriptome of Trypanosoma cruzi: a step closer to early diagnosis of neglected Chagas disease

tion of chemotherapy with benznidazole and nifurtimox in mice infected with Trypanosoma cruzi strains of different types. Cribado farmacológico

For this reason the purpose of this work is the description of fea- tures of this clone regarding growth kinetics of epimastigotes, metacyclogenesis in Grace medium, infec- tivity

drastic changes from normal epimastigote morphology in axenic cultures were observed in these transfectants (Fig. 3B, panel i) but not in wild type parasites, which were cultured

Key words: Trypanosoma cruzi - Calophyllum brasiliense - Mammea americana - coumarins - Chagas disease.. The protozoan Trypanosoma cruzi is the etiological agent of Chagas

The present article reviews the status of Chagas disease in Venezuela based on the detection of Trypanosoma cruzi infections both in referred patients with clinical

The slightly inhibitory effect of very high concentra- tions of NAOx or NPOx (10 mM) on glucose-6-phosphate dehydrogenase, HADH-isozyme and malic enzyme, and the lack of any

13: a: thin section showing the cytostome (CY) of an epimastigote form of Trypanosoma cruzi in the initial step of ingestion of gold-labeled transferrin (arrow);

Novel protective antigens expressed by Trypanosoma cruzi amas- tigotes provide immunity to mice highly susceptible to Chagas’ disease. Immune system recognition of