Interaction between CXCR4 and CCL20 pathways regulates tumor growth.

In fact, based on the high constitutive RANK expression in breast cancer specimens and cell lines, recent data suggest that RANK expression status of cancer cells determines

Inhibitory effect of bombesin receptor antagonist RC-3095 on the growth of human pancreatic cancer cells in vivo and in vitro. Inhibition of growth of HT-29 human colon

Taken together, these results suggest that IL-27 enhances the expression of TRAIL and TLR3 in human melanomas and inhibits their tumor growth in cooperation with poly(I:C), partly in

Fig 4: Hypoxia and a microdosage stromal cell-derived factor-1α (SDF-1α) augmented the surface expression of cognate recep- tor CXC chemokine receptor 4 (CXCR4) on mesenchymal

Proliferation and secretion of cytokines (IL10 and TNF a ) was determined in primary immune cells and the human cell lines (THP1, Jurkat E6-1 and Raji cell lines) stimulated

The compounds at the concentration tested in this work against human tumor cell lines do not shown significant cytotoxic activity on pheripheral blood mononuclear cells (data

Control฀cell฀lines฀and฀positivity฀values As฀ the฀ control฀ for฀ normal฀ expression,฀ we฀ used฀ the฀ K562฀ cell฀ line฀ (resistance-free฀ leukemic฀ cells)฀ and,฀

One critical component regulating the niche is stromal-derived factor-1 (SDF-1) and its receptor CXCR4 which regulates stem cell homing and, as we have recently demonstrated, plays