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Akt1 is essential for postnatal mammary gland development, function, and the expression of Btn1a1.

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Academic year: 2017

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Figure 1. Akt1 promotes postnatal mammary gland growth. Representative whole mounts of Akt1+/+ (A–D) and Akt12/2 (E–H) mammary glands at PND 11 (A,E), PND 25 (B,F), PND 50 (C,G), and PND 70 (D,H)
Figure 2. Akt1 mediates the terminal end bud, terminal duct and alveolar bud population
Figure 3. Akt1 influences gene expression patterns in the adult mammary gland. Microarray results were validated with qRT-PCR for the genes Btn1a, Akt1, Mtmr7, Muc1, Lbh, Dsc3, Pou2af, and Faim3
Figure 6. Akt1 is necessary for Btn1a1 expression following pseudopregnant hormonal stimulation

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