Silencing of glutathione peroxidase 3 through DNA hypermethylation is associated with lymph node metastasis in gastric carcinomas.

In the present study, we found that CMTM3 was frequently downregulated or silenced in testicular cancer cell lines and primary tumors (Figure 1, Table 1).We further performed

Silencing of FANCF in breast cancer cell lines led to significantly increased DNA damage compared with the cells treated with control shRNA (Figure 3).. Silencing of FANCF induced

We examined PTPN12 mRNA expression in five breast cancer cell lines using semi- quantitative reverse-transcription PCR, and detected PTPN12 protein expression using

In 7 gastric cancer cell lines, the expressions of Rac1 were higher than in gastric mucosal epithelial cell line (GES-1) [43], which was coincided with the phenomenon we found

To further validate the role of let-7f in gastric cancer cells metastasis, we compared the expression levels of let-7f in fresh human gastric cancer tissue specimens with

Consistent with the result that p21 protein was down-regulated in the gastric cancer tissues [23], we observed that HDAC4 promotes gastric cancer cell proliferation and growth,

Early gastric cancer is defined as lesions in the mucosa or submucosa, regardless of lymph node metastasis [ 14 ]. The absolute indications for endoscopic resection are

mRNA ( A ) and protein ( B ) expression of fi broblast growth factor receptor 1 (FGFR1) in normal human GES-1 cells and fi ve gastric cancer cell lines measured by RT-qPCR and