Re-circulation of lymphocytes mediated by sphingosine-1-phosphate receptor-1 contributes to resistance against experimental infection with the protozoan parasite Trypanosoma cruzi

infantum -infected hamster model showed that 51 days after the initial infection, amiodarone was unable to reduce the parasite burden in the spleen and liver when treated for

in the early acute phase of infection (5). Since a) IFN- γ produced by NK cells in the early acute phase of T. cruzi infection is important in mediating resistance, b) IL-12 has

Studies performed with rats and mice inoculated orally with Trypanosoma cruzi, obtained from blood of infected mice or infected feces from triatomid bugs, showed that the

The objective was to detect Trypanosoma cruzi infection in 32 children in Salta, Argentina, born to 16 chronically infected young women who were treated with benznidazole..

In spite of the fact that spleen seems to mount an immune response to the parasite, the immune responses in the regional lymph nodes were unchanged in both strains of

However, we observed a decreased CCL2 level and increased IL-10 levels in those infected animals treated with carvedilol, which impacted the reduction of the inflammatory

The analysis of parasite burden in the spleen showed that animals infected with the PP75 strain at 9 months after infection presented a higher parasite load if infected by the IC

There were 1 to 8 nodules present in 80% of the snails, counted after the challenged infection. When these snails were submitted to infection, with live non-irradiated mira- cidia,