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Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis.

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Academic year: 2017

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Figure 1. Sgpl1 expression in induced Sgpl1 Flox/Flox Cre +/2 mice. Two weeks after tamoxifen treatment, tissues from both  Cre-positive and negative Sgpl1 Flox/Flox mice (4 males and females, each) were analysed
Figure 2. Sphingolipid concentration in selected tissues of inducible Sgpl1-deficient mice
Figure 4. Normal T cell development, reduced splenic cellularity, and increased LN cell number in inducible Sgpl1-deficient mice
Figure 6. Protection of inducible Sgpl1-deficient mice in DTH.
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