Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion.

To evaluate the effects of ectopic expression of individual TRIMs on HBV replication in human hepatocytes, HepG2 cells were co-transfected with a plasmid containing 1.3 fold

Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and

Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by Lamivudine for chronic hepatitis B. PHYLIP (Phylogeny

In addition to their direct and indirect roles in the control of hepatitis B virus gene expression and replication, miRNAs are involved in immune response by controlling the

ELISA measurements of Shh protein concentration, flow cytometric analysis of cell expression, and chemiluminescence signaling assays in NIH3T3 fibroblasts co-transfected

these animals seemed to regain control of viral replication by day 4 p.i., which perhaps corresponds with the early entry of cells of the adaptive immune response as

Previous studies have shown a role for viral proteases in cleavage of key IFN signaling molecules [45]. For example, the NS3/4A protease of hepatitis C virus and GB virus B and the

In this study, we analyzed data of 50 patients with histological proven epithelial ovarian cancer, diagnosed and treated in Oncology Center in IbnRochd University Hospital