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Dysfunctional activation of neurotensin/IL-8 pathway in hepatocellular carcinoma is associated with increased inflammatory response in microenvironment, more epithelial mesenchymal transition in cancer and worse prognosis in patients.

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Academic year: 2017

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Table 1. Pathways enriched from differentially expressed genes between HCC tissues of high and low NTS expression by PathwayStudio TM .
Figure 5. All significantly differentially expressed genes between high and low NTS samples were put into Pathway Studio H to screen the candidates that were regulated by or interacted with NTS
Figure 6. Synchronous increase of NTS and IL-8 proteins in cancer cells closely correlated with the up-regulated inflammatory response in microenvironment of HCC
Figure 8. Synchronous increase of NTS and IL-8 in HCC correlated with worse prognosis and shorten survival of patients after surgery

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