• Nenhum resultado encontrado

The MicroRNA-217 Functions as a Potential Tumor Suppressor in Gastric Cancer by Targeting GPC5.

N/A
N/A
Protected

Academic year: 2017

Share "The MicroRNA-217 Functions as a Potential Tumor Suppressor in Gastric Cancer by Targeting GPC5."

Copied!
12
0
0

Texto

Loading

Imagem

Fig 1. The expression of miR-217 is downregulated in GC cell lines. (A) The expression level of miR-217 in four human GC cell lines (SGC-7901, HGC- HGC-27, MGC-803, MKN-45) and GES-1 was quantified using Northern blot.(B) The expression of miR-217 was asse
Fig 2. MiR-217 is downregulated in GC tissues. (A) The tissues were histological confirmed using H&E staining
Fig 3. miR-217 inhibits GC cell proliferation and invasion. (A) Real-time RT-PCR analysis of miR-217 in HGC-27 cells upon transfection ofmiR-217 mimic
Fig 4. miR-217 posttranscriptional reduces GPC5 expression by directly targeting its 3’UTR
+3

Referências

Documentos relacionados

In this study, using bioinformatic algorithms and luciferase reporter assay, we found that ZNF217 is a target of miR-203, a tumor suppressor miRNA. To explore the potential roles

In the present study, we provide evidence that miR-29c expression in high-metastatic 95D cell lines was downregulated when compared to miR-29c expression in paired low-metastatic

To confirm this hypothesis, we first examined the expression of miR-30c and found that the level of expression was significantly decreased in doxorubicin- resistant cell lines

Therefore, parallel to the quantification of the expression of miR-203 and miR-200c in tumor tissue from patients from Central Lisbon Hospital with breast cancer, the aim of this

In this study, we found that miR-124 was significantly down-regulated both in CRC-derived cell lines and clinical CRC samples compared with adjacent non-tumor colorectal

In this study, we identi fi ed the higher expression of lncRNA ANRIL in gastric cancer tissues than in corresponding non-tumor tissues, and it was also up-regulated in MKN-45

The aim of this study was to analyze the expression levels of the miRNAs miR- 146a, miR-155, and miR-326 in PBMC from T1D and healthy patients, and to estimate their possible

O objetivo desta pesquisa foi verificar o que se tem discutido sobre o eSocial como Tecnologia de Informação e Comunicação governamental, entre os anos de 2013 e 2018, quanto às