Genetic biomarkers for ALS disease in transgenic SOD1(G93A) mice.

As shown in Fig 1, our results show that plasma NfH levels increase significantly during overall disease progression between 65–120 days in the SOD1 G93A mouse model of ALS

Neste trabalho, comparamos neuroblastomas humanos transfectados com SOD1 G93A associada à ELAf (SH-SY5Y G93A ), e SOD1 selvagem (SH-SY5Y WT ) com células parentais (SH-SY5Y)

Laser capture microdissection (LCM) was used to study miRNA profiles in motor neurons of spinal cord tissue from SOD1 G93A mice, the best characterized model of ALS.. In

This will be achieved by using samples obtained from lumbar spinal cord of the transgenic mice carrying a human mutant SOD1G93A gene, B6SJL-TgN (SOD1-G93A) 1Gur/J (mSOD1), at two

ALS(SOD1 G93A ) mice treated with WN1316 showed a sustained motor performance compared to vehicle-treated ALS(SOD1 G93A ) mice at 20 weeks of age (late symptomatic stage) by

9 FERNANDES, Fernando – O processo penal como instrumento de política criminal, Coimbra: Almedina, 2001, pp.. 3 criminalidade se aplicam os acordos, ou ainda se pode ou não

Neste caso a variação do binário de travão é feita alterando a quantidade (massa) do fluido em circulação. Esta variação é controlada através de uma válvula à saída da

We addressed the potential role of miRs in the pathogenesis of DMD, consi- dering that, in muscle tissue obtained from mdx and transgenic mice ( a -and b -sarcoglycan knockout