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Influenza H5 hemagglutinin DNA primes the antibody response elicited by the live attenuated influenza A/Vietnam/1203/2004 vaccine in ferrets.

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Table 1. Ferret serum antibody titers from vaccination with iVN04 and VN04 ca.
Figure 1. H5 HA DNA vaccine construct. (A) Schematic diagram of H5-VN.tPA HA gene. The H5-VN.tPA DNA encodes the full length HA antigens with a human tissue plasminogen activator (tPA) leader substituting for the natural HA leader sequence
Figure 3. Serum antibody titers against homologous and variant H5N1 ca viruses following different vaccine regimens in ferrets.
Figure 4. Protection conferred by different H5 vaccine prime-boost regimens in ferrets

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