Methylobacterium
! " # $
% & ' ( )
* + %
,-.-Methylobacterium
/ 01)!21 03 $ 4 562
! " # " " $ " % &
'
4 *2
Methylobacterium
" ( " " ) * + + +
" " , - , " ! "
! Methylobacterium " "
& , " .( " " +
" / " , " 0 "& *
, , , " ! "
" " " Xylella fastidiosa 1 " & " * "
Methylobacterium( " " " 2 )
Quorum Sensing 3456, * 0 7( " (& " 3 89 6 "
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+ , ; ) " !
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< , " "
& 0 " " = Methylobacterium
" " , M. extorquens > ?/@ "
" ) " 3/ 6 " "
A " + , + " * " " " 0 "
Catharanthus roseus, ) " "
" X. fastidiosa , * " 2 " X. fastidiosa,
" " & ) : , * " 0
" & " /
89 ) + + M.
mesophilicum 5> ?/?( , + * "
+ ) mxaB, " "
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" + " 0 C acd5, + + "
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sss, + + " " , " + ,
phoD, " " " ,
89 " - + & *
Methylobacterium " : Citrus ,
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E
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Methylobacterium " ( " ) 89
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7 + " 8 Methylobacterium
& " ( " " ) " & + + + "
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Methylobacterium & " &G " " &
; " & G H & " &G & ;
" , & &G " 0 & & ( "& , & G "
& " G " " X. fastidiosa ;
I H & & " Methylobacterium( " " " G
H& ) G & 4 5 3456, H& "& 7( "G
& " 3 89 6 " ; " " H &
& , G G " " 0
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& , & H I H G , & " H
Methylobacterium " , + & " & " &
H & & + ) ; & " ) , H &
& " " G " ( " & " " &
" &
+ G, ; " " ) H & 2
+ + "& " H & G Methylobacterium &
" & 0 G " G
Methylobacterium " &G & " ,M. extorquens > ?/@
H " G ) " 3/ 6 0G D
" " " " G H + & & " " 0 &
" & Catharanthus roseus, ) H &
&G " " X. fastidiosa B & , H& " H & X. fastidiosa,
& " & & )G , & & " 0
& & & , & " " " 5 G & " 89
& ) + + & " H M. mesophilicum 5> ?/?(
H + & & " & " H & " +
) mxaB 3 & & &G & "
6C pat 3 + " + + &
" 0 6Cacd5 3 + + " & +
& 6 /) crt; sss, + + "
" , " + G, phoD, H & & " G H &
" 89 & + " & & G &
Methylobacterium " H & Citrus , & H " " G
H " &G " " , H + & &
" "" G H & & " " + , G H &
& " & & & )G " , & " Methylobacterium(
" ()G " G G 89
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N
, 42*29:2 $ 4 0* 1!2 $ 0!42 24Methylobacterium
4 %
& Methylobacterium " Citrus ,
Capsicum annuum 9 Saccharum officinarum 9 , 0
" " ( ) " 3 (" + ( Citrus limonia
"I I O Citrus sunki6, + + + " " ,
+ + ! ) " 0
" " "
(" + I , "
I 4 " 0 0 ,
+ " " ( ) 0 /)"
+ & " 3 > ?/@6,
(" + / I , +
+ + , + 0
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) , * 4 " "
, I
. * * " " 0
, & " > ?/@, > ?/ 5> ?/?,
& E/@ + " " ( )
" " " " " " I
Methylobacterium +
7 & : " + .
" " " " Methylobacterium + ;
" " ) " ! , + "
+ + " " " "
" . > > " *
Methylobacterium " 0 " ( ) "
+ " " " "
" (" + I , Methylobacterium
" & 0 " "
* Methylobacterium " 0 " & !
" " " " " " - " "
+ ("& + Methylobacterium C Citrus C ; " ( C
P
, 0!4 )42/!; 42*2!021 <Methylobacterium
"
& G &G " Methylobacterium Citrus
, Capsicum annuum 9 Saccharum officinarum 9 , " H & "I 3Citrus limonia "I Citrus sunki6, H
+ " " G " B & , & )
H + H & H " 0
" & " & & & H H &
Citrus limonia "I Citrus sunki, & " H G
H & Citrus sunki D " 0 & G, & H
& H + , & "I /)" & + "
G " 3 > ?/@6, & Q " & Citrus
limonia "I ; Citrus sunki, H + + "
7 & , " " &
"" & + , H +
& & " + H & & "I , &
& & & " Q & & Citrus sunki H
H& & " H " " G & & H& "
G & " > ?/@, > ?/ 5> ?/?, Capsicum
annuum 9 E/@ H & "I " " G
" & + " I H &, " GMethylobacterium
, H + G " 7 " H + &
G " "& " " Methylobacterium
+ ; " " ) , H& "& " &
"& + + H & H & & & "
> > G , H " & Methylobacterium
&G " G " "I + &
&G " " Citrus limonia "I Citrus sunki ,
Methylobacterium & 0 G " &
& Methylobacterium " 0 &G " G & & & +
" H & " " G "
, . 0
" " < ! "& +
& , 2 " &
+ & " "
" 38 99% 77 , NNKC 5 D>RC 7 S JC @PPP 6
B * , " " "
* " * " 0 0 3 ;99 TC 7 S J, NNK6
, " " " , + 0
* + )
" L " 35 D>RC 8>;5 ;/C 7 S J,
@PPP C S8; 5, @PP 6
" " , 2 ,
& " " + + ,
+ " + + % ) *
" + , * . + * + + & ,
38 > ;%C = 7 =/> //JC = 7 /95 5, @PPM6 / L
" = + ) " "
" - " , " &
3> 5/7 9D/ 8C % > ;7/R(> %/> , @PP?6 " ,
* " " + "
& , " " , + + , "
* + " 3 7> 8 , @PP?C 8 99 7 C 9 7$C
9 , @PP@C J9 / />C 9;B58; RC R 9 S; R, NMNC 5 D>RC 7 S J,
@PPP 6
" * " " & " ,
, , "
, " , " " ,
& A 0 3$9; J, NNFC J9 / />C 9;B58; RC R 9 S; R, NMNC
@
) ! " ! Methylobacterium " +. "
" " " =. +!
" " " " + ,
+ & A 3J /7;7$C % >>;5C 9 , @PP@C
9// , @PP?C % 8 ;T 7 , @PP?C %/> , @PPE 6 )
! 3% 8 ;T 7 , @PPEC % 8 ;T 7 , @PPN C 5T , @PP 6
, " " " , *
" " " + 3% 8 ;T 7 , @PPEC
% 8 ;T 7 , @PP?6
" " : " " " A " ,
& , "
) " . ME' @?? & " , " " /
5 , * " " KM,E@V " 3; $/, @P P6
9 + " " N PMP KFF
2 " + @P P, "
@@ ?@K 3; $/, @P P6
+ " " +. " " " *
) 37/=/5C >D%W 7/J, @PP?6 , : "
" A " + 0 + " ,
* " ( ( , 0
+ ) & * " , +
3 % > C =; /7 /C ;5 /99 , @PP 6, * , 2 "
* " " "
) + + " " 3 5 > C J/>5 /7, NN?6 " MFV
" " ) (" + 3Citrus limonia "k6 3 % /D
WX7; >, @PPF6 % ) + " ( ) ,
" & + " * * ! " : " <
" 3 >9 5, 5 D 8;C 7 ; , NNKC % /D WX7; >,
@PP 6
& + *
'
/ . " ( ) , +
" " " 0 * + + + <
" " " 3 > XW , @PP@C 9 = , @PPE6
" " + " , Methylobacterium
" "& "
, 2 + & +
Methylobacterium " " " " "
+ + " " , " " 6 +
Methylobacterium (" +
I C 6 + Methylobacterium " "
(" + I
4 7 &
7 (7J S , C %D5 8, % C 5 8;/>5 8, W C / 7/>, % C 5 8S ,
S % " " H Methylobacterium extorquens H &
, & " , " 0 & &
6 7 = % >, ) , + FK, F, EP@F(EP'@, @PP?
8;J >;, C W 5/ 8, % C T 7$, $ C 8;99; 5, C 7/95 7, 9 % /+
" > " H & " "
" 6 7 * " >, H , + P, N ?(N@E, @PP
9 5 8D9, 5 B C $;58, S C %;99/>, S C %T/>5, / S C 9; % 7, W " "
"& 6 7 * >, 9 , + @ F, EP'(E P,
NNP
% > , C =; /7 /, % % C ;5 /99 , 5 9 " "
? , , + @@, ('K, @PP
7 >/ /, B C >7/;> , > C 5 99/5, W B C % > 7, W C 9 /, C
R/=/ , W 9 C > XW , S 9 ( & 0 (
& " & + G Methylobacterium & & 0 &
& 0 " " G * " >, 7 H T I, + FK, M@(N',
@PPN
7 >/S5, W 8 C 8 >>;5, > B & " G &G "
" 4 8 7 +> + >, , + 'M, FE( MP, @PPP
> X9 , S 9 % " 7# %
E
' 3 $ " % & 6 O / " 5
" Y9 0 4 0Z, D + 5 , " " , @PPP
> XW , S 9 C % > 7, W C % 8/> 7; WD7; >, S C = 7 /95 5, W C = 7
=DD> /, W S 9 C R/=/ , W 9 + G &G " " &
" H & Xylella fastidiosa " %
* " >, , + ?M, ENP?(EN E, @PP@
> XW , S 9 C 5 >; J;5, 8 C >> 5 , = C $D;9 >(=;9 5 , ; C
R/=/ , W 9 = G " H &G " "
" "I 6 7 * " >@
H , + EK, @@N(@'?, @PP
5$8 >, 8 7 C R 8;>, R C >58 , % C J8 9;4, > & H +
" " ) G & 0 " & H &( " + Brassica
juncea9 D > 7 , , + 'F, @' (@'K, @PP@
55D% [\ , 9 C 9 = , C ; 5, B C R/=/ , W 9 C %/7 /7, W %
+ " " " " " "
2 E F , , + EE, F, FP'(F P,
@PPN
R/=/ , W 9 % " " ; %/9 , ; 5 C R/=/ , W 9 3/ 6
% " W L /% > (% , NNM " E, K(
'K
R/=/ , W 9 C % 8/> 7; WD7; >, S C />/;> , W C > XW , S 9
/ &G " " + H " " " + " "
6 7 + >, = , + ', EP(?F, @PPP
> 5 , W C % 98/;> 5, / C 7R , ! !
. " A " = @ P W " D , NN@
>$/5, > 5 C 9%/; , B W C 5 > 7 >;, C % 8 , % C >= 98 , 5 C
9/ B;98 , 8 C $D;9 >(=;9 5 , ; ; //% > / 7 *
" + < " " +
" ? , , + @ , @PF(@@E, @PPP
>; , W % C 5 J, > % C 5;9=/>5 7/, 5 > G " "
" " G " 0 "
% * " >, , + FK, F'F(F'M, NN
>9 5, / B C 5 D 8;, / 5 C 7 ; , 9 G =
F
5 > , % C J/>5 /7, / ; ! "
2 = ! " 3Citrus sinensis39 6 "I6 + " # , " " , F', + @', NN(@P', NN?
8 7S T, C 58;58; , % C 7 ;>7, W C WD7$S;> 8, 5 C % >J8 %, W C U; ,
$ C 8 99, B $ / &G " " 0 &G "
" H & H &( & 0 " D >
* % , , + '', M (MM, @PPP
7> 8, D / J/>5, $ W % C B9 >/5, = C $ > ^ ( $D5 ^7, C W J , $ C
% D 8, B C 7/S% 7, % C ;/ />5/, % W C ;755 , C R , % W C D$;7,
C 5 8 BB> 8, D C 7, W C S/7 /8/77/, C R;%%/>9;, 9 C % D 8(% 7;,
G * G* " 0 , 5 ,
+ N, N?@( PK , @PP?
/>/;7/>, W C 9 7;, = 9 C 9 7;, W 9 % 7
" H7 % /% > O 5 ;,
NNF, + ?P
/7/ J, 5 C S/;, $ C J9 />, W S / " H &(
& 0 " G "& D , S & , + EE,
E ( E', NNM
B/>>/;> , C 4D/ ;7/, % C 9 = , C , 5 C R/=/ , W W C > XW ,
S 9 + G &G " " Eucalyptus " " 0
GPantoea agglomerans. D * * " > , , + @MK, , M( E, @PPM
B>/; 5, 5 5 C $D;9 > =;9 5 , ; > 0 " " "
" " 4 & , = , + @M, NMK(NNE,
@PPE
$9/77, > C ;9S > 8, % W + & 0 * "
, ) , + @, ? ( ?K, NMF
$9; J, > & & " H & G ( + "
6 7 * " >, H , + E , PN( K, NNF
8 99% 77 W C 4D (8 99% 77, C % 8 BB//, S B C J9 / />, W S
" &G " " 6 7 * " >, H ,
+ E', MNF(N E, NNK
8 > ;%, > C = 7 =/> //J, 9 5 C = 7 /95 5, W "
&G & H & ! * " >,
?
8/D/>, 8 C 5% 99 , J " " & 3 $$/6
" & G " " ,
; = 7 /95 5, W , S/99;7$ 7, / % 8 , >/= >5, W 3/ 6* % " > 7 H T I % " II , NNK 'F'('K'
8 99 7 , % C 9 , W B% & " &
&G G & 2 _ 4 8 7 +> >
* >, , + EF, NK(@@P, NNE
8 99 7 , % "" 0 & G "G I " G
_ +> >, 7 + T I, + F, M?F(M?M, NNK
8 99 7 , % Methylobacterium 4 4 + $ % ,
+ , + , @PK(@ ', NNK
8 99 7 , % C 9 7$, > 9 $ C 9 , W Methylobacterium &G
" + + " ( I H & & _ ; 9;77 S, 5 / C 8/ 8 ( ;7 >,
/ ; C /99; , = W 3/ 6 +> + * " >, 5 , @PP@ @F( 'F
; $/ B O $ / " " . ( $ / /; $/,
/, $> ( 9 + 5 . " " , B + @P P
+
& ]]HHH + ]& ] " ] " ] " ] ] & `
" P@ , @P P
J $ , 8 C % 7 , 8 C 7 J , B C S 7 /, C J 7/J , 5 C % >;5 J;, 8 > "
" &G " " * " % , 5 , + @E,
FE( ?@, @PPN
J8 9; , C >58 , % C R 8;>, R 5" H &( & 0 "
+ H & G H& 6 7 * " >, ) , + N?,
EK'(EMP, @PPE
J 9T /= , % C R J8 > 8/7J , 7 5 C > 7;7 , 7 = C >DJ = 5 = , / C
;= 7 = , / $ C 9/J5//= , = = , > 5/7J;, T C D>T 7 =, T ; H &
& + G " + &G & " " 4
6 7 +> >, 7 H T I, + EM, F EOF K, @PP
J9 / />, W S C 9;B58; R, > C R 9 S; R, / B ( + "
& " " " + G ! + >, , + K, 'N(E',
NMN
J /7;7$, > 9 C % >>;5, > C 9 , W >7 & " H( + (
0 " Methylobacterium 6 7 >, , + ME,
K
9 = , C > XW , S 9 C % > 7, W C % 8/> 7; WD7; >, S C R/=/ ,
W 9 ; " H &G " " " & &G & "
" Xylella fastidiosa, " " + "& * " >, ) , + 'N FF(FN, @PPE
9//, 8 5 C % 8 ;T 7, % C J;%, S C 8 ;, 5 W C 8D7$, J T C 5 , % &G " & " G H & " 3Oryza sativa9 6 G
" &G & 7@( ) &G & " > D >
7 , , + E@, EP@(EPM, @PP?
9;B58; R, > C J9 / />, W S C J R9 S5J;, % C 5;% 75 7, C >95 7, W C
; ;7$, / % C R 9/5J , ; $ H & " 3 ( 6 G
Pseudomonas putida " " 6 7
* " >, H , + M, P@( P?, NMK
9 /ST JU, C = 7$> 75=/9 , W C > / D5, B C % >/, / > C $8 =;, 5 C %/R$/ T, % C = 7 /> 9/9;/, / &G " " & "
" 4 8 , , + @ , FM'(?P?, @PP@
% ;7> T, W C J9 / />, W S G " &G " "
H & H " " 6 7 * " >, H , + E ,
MNF(N , NNF
% 8 ;T 7, % C 7$DR8 9;, 5 C 5/7 8;9JD% >, % C 5/58 >;, 5 C 8D7$,
8 T C T 7$, W C 5D7 > %, 5 C 5 , % $ H & "
G " " " " + P(EK 3Oryza sativa9 6 GMethylobacterium
7 % , , + EF, E, ' F('@E, @PPE
% 8 ;T 7, % C 7$DR8 9;, 5 C 9//, 8 5 C 5D 7 > %, 5 I(
" + &G & " " "" , H & G
" " M?P'@ 3Saccharum officinarum9 6 > D > 7 ,
, + E , 'FP('FM, @PPF
% 8 ;T 7, % C 5D>/58 >/ T, = C 7 7 8 7, > C 5/7 8;9JD% >, % C
7$DR8 9;, 5 C 5D7 > %, 5 C 7$%;7 5 H &(
Methylobacterium " 3Arachis hypogaea 9 6
" H & & * " >, 7 H, T I, + F', @KP(@K?,
@PP?
% 8 ;T 7, % C J;%, T C 7$DR8 9;, 5 C JS 7, 5 S C 5 7$, % 8 C >TD,
W 8 C $ , 5 W C J , 5 C 5 , % Methylobacterium oryzae + , ", I(
, " + G &G & ", ( "G" (9(" )G
" " " 0 6 7 > %
M
% 8 ;T 7, % C 7$DR8 9;, 5 C JS 7, 5 S C 5 , % Methylobacterium
phyllosphaerae 7 + , I( , " + &G & &
&G & " 0 6 7 > % >
* " >, > L " , + FN, @@(@K, @PPN
% 8 ;T 7, % C 7$DR8 9;, 5C 5/7 8;9JD% >, % C 5D7 > %, 5 C 5 ,
7 ( H & G &G & " " "
* " 4 +, , + ?E, E( @P, @PPN
% 7 , 8 C % >;5 J;, 8 / &G " " " * "
% , 5 , + @', PN( K, @PPM
% 7 /5;7 5, / C 7 />> , C 5 , / C B> 7 15, W C 9/% 7T, W C
99 >/7 /, ; C % > $>/$ , " " & H
"& " & " 0 * " >,
" , + F, ?N( KF, @PP@
7/=/5, % B C >D%W 7/J, % 5 ?
( ,-.I @' + @PP? > " /% I /
+ aHHH " / * + b + / b / b
b @P Fb /75 ; 7/ ` " F @PPN
%/>, R 5 C % 9;7;, > C $/>8 > 5 7, " 0 G I(
" + &G & " " 3 B% 6 D * * " > >, , + E?, ' N('@?, @PPE
%/>, R 5 C % 9;7;, > C > />$, C $/>8 > 5 7, ; ('( " " "
" G I( " + &G & " " ) 8 +
4 , "& , + E', N'(N?, @PPE
;99 T, = J C 7 S J, W ; " G, , G "
+ H & &G " &G " " 0
3Lycopersicon esculentum96 " H & "
6 7 * " >, H , + E', 'FE('? , NNK
% /D WX7; >, W ( ) ; % 5 WX7; >, C / 7/$>;, W C ; ,
> % C % /D WX7; > , W ; B @PPF " E ? ( PE
% /D WX7; >, W > "I " & " " & 5 5
; 7$>/55 B 8/ ;7 />7 ; 7 9 5 ;/ T B ; >D5 7D>5/>T%/7, ? ,
@PP , > c / /) " ,
@PP KF(M@
> 7R , & " + & 0 " / 3Alnus
N
4D (8 99% 77, C J9 / />, W S ; " " " 0
& " &G Enterobacter asburiaeW%@@ "
6 7 * " >, H , + E@, EE( FE, NN?
4D/ ;7/, % " H " G G
J BSaccharum C @P P N? 3 ! " 6 O / "
5 " Y9 0 4 0Z, D + 5 , " " , @P P
> >;$D/R , 8 C B> $ , > & & 0 " &
H & + >, , + K, ' N(''N, NNN
> 5/7 9D/ 8, % C % > ;7/R(> %/> , / " &G &
" H & & * * " 0 , 5 , + N, M,
M@K(M'K, @PP?
> 55/ , 0 G G J " @P P
N? 3 $ " % & 6 O / " 5
" Y9 0 4 0Z, D + 5 , " " , @PPM
>TD, % C J;% W C 8 ;, C J;%, 5 8 C >J, 5 ; + " "
" " G Paenibacillus polymyxa/?M G
, , + 'N, @M@(@MN, @PP?
5 7 5, % 8 9 C % >; 7 , > 9 > C % > , > C 7 > /, $ C S;99 ;7 ,
9 C 9;% , $ " " " + + Heliconia
psittacorum9 B ; + , 5 , + '@, @, (M, @PPF 5/7 8;9JD% >, % C $ =;7 5 %T, = C 77 D>7 , J >
"& " G G &G Paenibacillus 8J ( F
* " >, 7 H T I, + FF, @F(@N, @PPK
5/7 8;9JD% >, % C % 8 ;T 7, % C 5D7 > %, 5 C J 77 ;T 7, 5
; " " 0 H & " Methylobacterium S &
( H & " 3Oryza sativa9 + (E'6 * " 4 +,
, + ?E, N@( PE, @PPN
5 /> , 7 C B>/; 5, 5 5 C %/9 , % C > 7;, / > 0 " "
" 0 0 " , " " " " 4
& , = , + 'P, @@F(@'E, @PP?
5 D>R, = C 7 S J, W / &G " " & 0 " &
* " G & " " H & " >,
, + F, M'( NP, @PPP
5 D>R, = C 8>;5 ;/, > C 7 S J, W " &G
+ G " " 4 8
@P
5T, C $;> D , / C W D> 7 , C $ > ; , 7 C S;99/%5, C / 9 WD ;/, C >;7, T C 7/T> , % C $;99;5, % C ;=;7(% 55 7, C >/TBD5, % &G & "
Methylobacterium " ) G H & 6
7 >, , + M', @ E(@@P, @PP
T % , 8 C 7 8 7T, C 9; 5 > %, % / "
mxa Methylobacterium extorquens % G " D *
* " > , , + ??, (K, NNM
= 7 J/7, C />/5, % C T, 5 9 C T %, W % C 5 87 >, W 9
Methylobacterium populi nov, + ", I( , " + G
&G & ", & ( 0 " 3Populus
deltoides)nigra 7'E6 0 6 7 > % >
* " >@ I , + FE, N ( N?, @PPE
= 7 9 7, 9 C JJ/>, 8 % 5 & 0 " ( " ;
J> 7, W =;55/>, W S 3/ 6 @PPE 4 > 5 = , @MK(
''P B/" " , + ?M6
=/$ , B / C = (>; 99, % C 5 , BC DT/>, W / &G " " Coffea arábica9 6 7 * " >, S & , + EF, 'K ('MP, @PPF
=/>% , 5 C 9 8 , W J C >; 8;, J /+ H &
" 0 G &G " 0 & H " 6 7
+ >, = , + N , @K( E , @PP
5 =J/9 = , / C 8/> T7 5/= , C ;7 , 5 $ C 7/ >5 =, ; "
" H & "& " " ) * "
4 +, , + ?@, ?N(K?, @PPK
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= % >, ) , + F@, EMK(F , @PP
R > 7 ;, % / C 7W >, 5 $ 8 C /8J /;, B C % 5 =;, 5 C B > J8;, > C
$8;$8;, 5 " " " 3Magnaporth oryzae6 G
Streptomyces sindeneusis @?' & % 6 7
@
K L 4 :2 ; ! 4M 2) $ βG.@NG 1$2) 0 1 * Methylobacterium extorquens 2 2103 9:2 1$2DO!0 $ Catharanthus roseus
4 %
Methylobacterium extorquens > ?]@ "
Citrus sinensis = , " Xylella fastidiosa. / "
" ) β( ,E( " 3/ 6
Bacillus pumilus. & , >/$9 , 0 Catharanthus
roseus, " , " " X. fastidiosa
3 & " = 6 & , +
" " A " + 3%/=6 B + * &
>/$9 " 0 " C. roseus, , " *
" & / &
>/$9 + & " 0 +
) * M. extorquens X. fastidiosa &
+ ) . " C. roseus, &
/ " * 0 Methylobacterium " =
. + .+ + < " " " " .
+ ("& + Methylobacterium extorquensCEglAC ; " ( C " CXylella fastidiosa
K ; ! 42 2)2 L 4 021 2D βG.@NG 1$2) 1 01
Methylobacterium extorquens 1$ 1$2 ;<!0 2 2103 !021 2D Catharanthus roseus
"
Methylobacterium extorquens > ?]@ H &G " "&
Citrus sinensis & H G = , " G Xylella fastidiosa &
" H " G ) & G "
3/ 6 Bacillus pumilus. & , >/$9 , H "
Catharanthus roseus, & " H & X. fastidiosa 3
" " G = 6 & & H + G "
" " " G 3%/=6 ; H + & & >/$9 " 0 &
" C. roseus, H& & , " & & H G G
G & & & , & H +
H & & )G + & " & M. extorquens X. fastidiosa " & & & )G C. roseus, H& & G " " H & & &
& " & G Methylobacterium "
@@
J GH Methylobacterium extorquensC / C " ( " C 5G " " CXylella fastidiosa
K . 0
0 + " *
" & " , 2 " /
" ( +.
& " " / " 7 " ) ,
" " ! Methylobacterium " "
" " 3 > XW , @PP C > XW , @PP@C 8 99 7 C
9 , NNEC %/>C % 9;7;C $/>8 > 5 7, @PPE6, +
" " + / " 3% 8 ;T 7 , @PP?C 9// ,
@PP?6 / " , Methylobacterium " " !
" " ( ) 3 > XW , @PP 6
Citrus , " = , "
" X. fastidiosa 3 > XW , @PP@6 , + 0
" " ! X. fastidiosa,
" " = "
5 & " "
" X. fastidiosa, = & "
Methylobacterium & / &
. + Methylobacterium , !
* . " 3 > XW , @PP@C 9 = ,
@PPEC 5 7 5, @PPF6 ,
Methylobacterium X. fastidiosa 0 in vitro, * ,
" , " "
Methylobacterium 39 = , @PPE6 , 3@PP?6
@'
" 0 C. roseus Nicotina clevelandii, "
Methylobacterium X. fastidiosa
) & " , + "
+! + + " "
) " * + " " "
0 " 3B 8/T , NN C 9 % /9 , NNEC
% 5;7 , NNF6 > " , % ) 9 3@PP 6 + + , "
M. extorquens % , + ) *
" mxaB 3 * " " 6,
" " * +
& " " 3 7 8 7TC $8 58C
9 J/ , NNEC 9; 5 > %C %D>>/99C 9 7, NN@C = >8 9 , @PP@6,
" Methylobacterium &
3 7 (J7 S , @PP?C 5T , @PPF6, " )
& Methylobacterium , " M. extorquens
" " " ,
" + @ 3 > 5/7J C ; 7 = C > 7;7 , @PP 6, & )
3 8 6 3 D>4D/C %/>9/ DC $> 9/ D, NNFC J > J = C
8;5 5/> > C 9; 5 > %, @PP@6, " 3= 7 ;/7 , @PP'6
& A 3J /7;7$C % >>;5C 99 , @PP@6 , "
Methylobacterium &
" , " " * " " "
& " , & 3@PPM6 "
) cry B. thuringienses M. extorquens "
Bombyx mori 7 , " " +
" * "
/ 0 " * " " * &
" " " " , * "
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@E
X. fastidiosa " $ ( + )
& , * " = " 3 8 7$ , NN'6 "
+ 38 J;75, NMN6 1 + ,
" < " " , * * X. fastidiosa
+ ) " " " 3 D> /99C
B;79 T, NKNC D> /99C 8 J;75, NN?C > 55/ ; , NNP6 &
" " X. fastidiosa
) " 3/ 5 6 3 5;9= , @PP C 5;% 5 7 , @PPP6
+ . % " " / A " = 3B 6,
/ 5, 3 5;9= , @PP 6,
" " * , + < +
) . " * , " " + "
, " " , + ,
" , = , " &
& 3% 8 , NN@C % 8 , NNEC > 55/ ; ,
NNP6
B ( / " X. fastidiosa " + ) Citrus B / S J 2 3/5 94/D5 6
" +. " "
! " / 5 3 5 /> 7C 5 /S > C
$>//7 />$, NNN6, " " "
@F
/ 5 " "
" ! Bacillus ! " " " "
/ 5 7 I 3 NNN6 " + "
0 ) Bacillus & $9 , *
0 , ( ,E ( " , * "
0 9 3@PPF6, +
" " ! Bacillus 3 L2 , @PP 6 * <
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5 0 + L2 3@PP'6, " 0 "& * X.
fastidiosa " , Methylobacterium " "
0 & ) 0
" ) " " , $ 3@PPN6
" M. mesophilicum 5> ?/? )
" + 3$B 6, 0 " "
C. roseus, ) " 0 "
Bucephalogonia xanthophis, + X. fastidiosa pauca
* " +
& , " "& * C.
roseus , " " "
" " X. fastidiosa pauca / & 0
, M. extorquens > ?]@, & " , "
" ) $B C. roseus
* , " + " M. mesophilicum 5> ?/? 3$ ; , @PPN6, M.
extorquens > ?]@ " 0 & 2 + + M.
extorquens > ?]@ " " " " " X. fastidiosa,
" " )
@?
4 7 &
7 (7J S , C %D5 8, % C 5 8;/>5 8, W C / 7/>, % C 5 8S ,
S % " " H Methylobacterium extorquens H &
, & " , " 0 & &
6 7 = % >, ) , + FK, F, EP@F(EP'@, @PP?
7 >/ /, B C 9 = , C $ ;, 5 C > XW , S 9 C % 8/> 7;, S W> C
= 7 =/> //J, 9 5 C = 7 /95 5, W C R/=/ , W 9 % G &
" H Methylobacterium mesophilicum Xylella fastidiosa
6 7 * " >, H , + F@, E N(E@?, @PP?
7 8 7T, C $8 58, % C 9 J/ , B & " " &
&G * " G * *
+ % 6 , 9 , + 'PE, ??F(?KE, NNE
> XW , S 9 C% 8/> 7;, S W C $D;9 >(=;9 5 , ; C >> 5 , = C
5 >; J;5, 8 C R/=/ , W 9 = G " H &G "
" " "I 6 7
* " >, H , + EK, @@N−@'?, @PP
> XW , S 9 C % > 7, W C % 8/> 7; WD7; >, S C = 7 /95 5, W C = 7
=DD> /, W S 9 C R/=/ , W 9 + G &G " " &
" H & Xylella fastidiosa " %
* " >, , + ?M, ENP?(EN E, @PP@
R/=/ , W 9 > XW , S 9 $ " G " + &
& & " " 4 8 * 4 +, , + FEE, @@'(@'',
@PP'
D>4D/, C %/>9/ D, T C $> 9/ D, 8 &(" ( G " G(
β(&G )G G 3 8 6 & GMethylobacterium extorquens "
& &( " ( 8 * " > + >, , + EE,
'?K('K?, NNF
8 7$, W C $ >7;/>, % C R>/;J, 9 C > 55/ ;, = C =1, W %
" " & )G ( " " " + "&
" Xylella fastidiosa * " >, 7 H T I,
+ @K, 'K( E@, NN'
8 ;, T W C 9 S>/7 / $>;$ > /7, W C 19 7$/>, 9 C % >/9, 9 C D>4D/,
C % 55 7, 9 C $> 9/ D, C %^$D/R, " " " " G
Bacillus thuringiensis G & &G &Methylobacterium extorquens
@K
> /, S C >8//%, 5 /" G & &G & " " +
" D * * " > >, , + ?@, @E'(@FP, NMN
5 /> 7, W S C 5 /S > , 5 C $>//7 />$, / "
" " " , S & , + ME, ' M( '@@,
NNN
5;9= , B > C =/ >/, 9 C J/% />, / 9 C 9/; /, C >>D , B & Xylella fastidiosa ) G ""& G + + "
& " G D * * " > , , + @P', ?F( K , @PP
=;5, % W C B>/7 8, S W C 5 8 , 7 S ) " " " " H &
& G "& * " >, 7 H T I, 'PN('@E,
NM
/ 5 DR , C J; , % C />/;> , / C 9/ (B;98 , 8 C % 8 ,
% /) & " G( Xylella fastidiosa +
* " >, 7 H T I, + FP, @@'(@@M, @PPF
B 8/T, W S C ;% J, % > C % 5;7 , 5 B C T9 >, W % C >;5 7, 5
$ " G &G " " G G ;
7 >/S5, W 8 C 8;> 7 , 5 5 3/ 6 * " > 7 9 5 (
= , NN EP (E
B/>>/;> B;98 , 5 C 4D/ ;7/, % C $ 5, C > 55/ , C 9 = ,
C R/=/ , W 9 C > XW , S 9 / &G "Methylobacterium extorquens
) & G β( ,E( " Catharanthus roseus
= @P P
B;$D/;> , % % C 9 > %//, 9 C %D>>/99, W C $> 9/ D, %;$D/R,
" " G & &G & " "
Methylobacterium extorquens D * * " > , , + N', NFO@PP, @PPP
$ ;, 5 C 9 = , C 4D/ ;7/, % C D>; , % C 9 /5, W > 5 C > XW ,
S 9 C %;99/>, C R/=/ , W 9 Methylobacterium mesophilicum
GBucephalogonia xanthophis " " G =
& !+ 6 7 * " >, 5 , + EK, E, EEM(EFE, @PPN
8 99% 77, W , 4D ( 8 99% 77, , % 8 BB//, S B , J9 / />, W S
" &G " " 6 7 * " >, H ,
+ E', MNFON E, NNK
8 99 7 , % C 9 , W B% & " &
&G G & 2 _ 4 8 7 +> >
@M
8 J;75, 9 Xylella fastidiosa)G O " &
4 8 7 +> + >, , + @K, @K (@NP, NMN
J /7;7$, > 9 C % >>;5, > C 9 , W >7 & " H( + (
0 " Methylobacterium 6 7 >, , + ME,
M'@( ME@, @PP@
J > J = , 7 C 8;5 5/> = , 9 C 9; 5 > %, % / G( (&G )G G G & & " + &G &Methylobacterium extorquens %
" gap ,gap@P, pha> 6 7 >,
, + ME, ? KE(? M , @PP@
9 = , C > DW , S 9 C % 8/> 7; W> , S C R/=/ , W 9 > " " G Xylella fastidiosa, " " +
"& * " >, ) , + '', 'P@('P?, @PP
9 = , C > XW , S 9 C % > 7, W C % 8/> 7; WD7; >, S C R/=/ ,
W 9 ; " H &G " " " & &G & "
" Xylella fastidiosa, " " + "& * " >, ) , + 'N FF(FN, @PPE
9 = , C 9;, S C R/=/ , W 9 C 8 > D7$, W 5 > , " "
* + G & " & &G " " Methylobacterium
mesophilicum 6 7 * " > * + , , + ?F, F'F(
FE , @PP?
9 = , C > XW , S 9 C R/=/ , W 9 /+ &G " " 0
Citrus sinensis Catharanthus roseus G &G " " !+ 6 7 * " >, 5 , + EF, ( E, @PPK
9 % /9, W 5 C 7 />, W 9 C ;% J, % C J/99T, W 9 C 7 />5 7, W W C D> 7;, C B D9J/ W>, W 5 C D>7/>, W ; + " , )
G & cry 3"6 Bacillus thuringiensis Kurstaki "
Clavibacter xyli cynodontis % * " >,
S & , + ?P, FP (FPM, NNE
9//, 8 5 C % 8 ;T 7, % C J;%, S C 8 ;, 5 W C 8D7$, J T C 5 ,
% &G " & " G H & " 3Oryza sativa9 6 G
" &G & 7@( ) &G & " D > 7 , , + E@, EP@(EPM, @PP?
9;, S C >; W S C /;U/;> , C %;> 7 , = 5 C T>/5, W C B> 7 ,
B C 5 , % $ " "& " G Xylella fastidiosa
" , $ , 5 , + MF, F, FP (FPF, @PP
9; 5 > %, % / C %D>>/99, W C 9 7, 8 3/ 6 % & & 0
@N
9;% , C 4D/ ;7/, % C BD7$ > , % 8 C 7 >/ /, B C > XW , S 9 C 5;9= B;98 , % C ;RR;> 7;J9/;7/>, C R/=/ , W 9 % " " " 0
+ ( ,E " &G " Bacillus pumilus
+ >, , + ?M, FK(?F, @PPF
% 8 , % C >D5 , / C 4D $$; , W C 9 $ , % % C ; /99;, % C
BD>9 7;, > " - & " 2 "
= 4 D A , 9 , + ?, F'(
FK, NNE
% 8 , % C 5;9=1>; , W 9 C ;5 , > C >;5 B 7;, % C / B;9 (
5 >;78 , W + + < " +
" 3 = 6 ? , , + ', F F(F' , NN@
% 8 ;T 7, % C 5D>/58 >/ T, = C 7 7 8 7, > C 5/7 8;9JD% >, % C
7$DR8 9;, 5 C 5D7 > %, 5 C 7$%;7 5 H &(
Methylobacterium " 3Arachis hypogaea 9 6
" H & & * " >, 7 H T I, + F', E, @KP(@K?,
@PP?
% 8 ;T 7, % C 7$DR8 9;, 5C 5/7 8;9JD% >, % C 5D7 > %, 5 C 5 ,
7 ( H & G &G & " " "
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% >U, W C 9; 5 > %, % / + + + (& (
+ " &G & & $ ( + " * " >, 7 H
T I, + EK, E E(E N, @PP
%; 8/9;, B " &G " H 0G H &
&G G ! , J , + ?, E E(E N, @PP
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% 7;/>, W % C 9;7 S, 5 / + + G "
" " 7 + 1
%> 7 7 7 % @S & , + PP, FNKK(
FNM@, @PP'
% 7 /;> , C >/7 D ;7, W C W $ D/;U(/=/;9 > , 5 C T>/5, W C $ >7;/>,
% C =1, W % Catharanthus roseus, ) & & "
Xylella fastidiosa $ , 5 , + MF, @E?(@F , @PP
%D> 58;$/, C 5J $, B + H & G H &
'P
7 7J ;, 8 C 8 58;% , S C %;J;, 8 C J S ;, 5 C J D5 JD, % % " G
G ""& G 0 0G " ) & G 0 G
Bacillus 5 $9 % * " >, , + ?F,
?, @F@P(@F@?, NNN
7/%/ / J(% >58 99, % C % " 7 9 , > C B> 7R/7, W W C
S W ;/ 8 S5J;, 9 C B 99, > % & + / 0G " "
( & & & ) " " "
+ +> >, > "I+ , + PM, 'FN( '?M, NNF
7/S% 7, J 9 , 9%/; , > , D> /99, 8 , 9;7 S, 5 / D
" G Xylella fastidiosa" 0 Vitis vinifera
% * " >, , + ?N, K' NOK'@K, @PP'
%/>, R 5 C % 9;7;, > C > />$, C $/>8 > 5 7, ; ('( " " "
" G I( " + &G & " " ) 8 +
4 , "& , + E', N'(N?, @PPE
D> /99, 8 C B;79 T, 8 /+ " " " " d
" G & & & +> + >, 9 " , + ?N, 'N'(
'NF, NKN
D> /99, 8 C 8 J;75, 9 B )G ( " &
4 8 7 +> + >, , + 'E, ' ( F , NN?
4D (8 99% 77, C J9 / />, W S ; " " " 0
& " &G Enterobacter asburiae W%@@ "
6 7 * " >, H , + E@, EE( FE, NN?
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" "& & 6 7 * " >, H ,
+ E', FKK(FM@, NNK
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4D $$; W C / 7/$>;, W " " )G d
"& + , + %
4 0P % , , + ' P, 'EF('EN, NNP
>TD, % C J;% W C 8 ;, C J;%, 5 8 C >J, 5 ; + " "
" " G Paenibacillus polymyxa/?M G
, , + 'N, @M@(@MN, @PP?
5 7 5, 9 " H7
7 Curtobacterium flaccumfaciens 7#
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'
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>> 5, % 8 C 7 >5;, / C > ;7, 5 C =1, W % C >; 7/5, % > 5 C D/7 , % > C % >$ , C % >$ , 9 / C >> > , % C >>/>, 8 C
9 D , 7 C 9 % , C 5 , B B C 5 , % > C 5 (7/ , % C
D ;78 , 9 9 C >;5 B 7;, % C ; 5(7/ , / C /7 , C /;( >>T, 8 C B ;7 7;, C B/>>/;> , W 5 C B/>>/>; , = C B/>> , W C B> $ , W 5 C B> 7[ , 5 C B> 7 , % C B> 8%/, % C BD>9 7, 9 > C $ >7;/>, % C
$ 9 % 7, $ 8 C $ 9 % 7, % 8 5 C $ %/5, 5 9 C $>D />, C 8 , 9 C
8 8/;5/, W C WD74D/;> , % 9 C J/% />, / 9 C J; W;% , W C J>;/$/>, W / C JD> % /, / / C 9 ;$>/ , B C 9 % ;5, % > C 9/; /, 9 C 9/% 5, / $ % C
9/% 5, % = B C 9 /5, 5 C 9 /5, > C % 8 , W C % 8 , % C
% /;> , % 7 C % /;> , 8 % B C % >;7 , 9 C % >4D/5, % = C % > ;75,
/ 9 C % > ;75, / % B C % 5DJD% , T C %/7 J, B % C %;> , / C
%;T J;, T C % 75 /;> (=; >/99 , C % 7, 8 C 7 $ ;5, % C
7 5 ;%/7 , 9 C 7/ , 9 / 5 C 78 7; W , C 7 >/$ , B $ C 7D7/5, 9 C
9;=/;> , % C 9;=/;> , % C 9;=/;> , > C 9%;/>;, C >;5, C /;U , > C />/;> , $ C />/;> W , 8 C /54D/> , W C 4D $$; , > C > /> , $ C > >;$D/5, = C % > 5 , W C > 5 W , = / C 5#, > $ C 5 7 /99;, > = C 5 S 5 J;, 8 / C 5;9= , > C 5;9= , % C 5;9= , B > C 5;9= , S C 5;9=/;> , W B C 5;9=/5 >;, % 9 R C 5;4D/;> , S W C
5 DR , C 5 DR , C />/7R;, % B C >DBB;, C 5 ;, 5 % C 5D8 J ,%
8 C = 99 , 8 , = 7 59DT5, % C =/>W =5J;( 9%/; , 5 C =/ >/, 9 C
R $ , % C R R, % C %/; 7;5, W C 5/ D 9, W & * " &
& Xylella fastidiosa.1 , 7 H T I, + EP?, F ( FK, @PPP
5 > 9, W J % " 7# 7# ? BGlycine
maxC H7 G @PP' KE 3
$ " % & 6 O / " 5 " Y9 0
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5T, C ;%%/>5, W C J7;/B, C = >8 9 , W % &G & "
+ Methylobacterium extorquens " 0 Medicago
truncatula " + " % * " >,
, + K , K@EF(K@F@, @PPF
'@
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mxa Methylobacterium extorquens % G " D *
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&G G * " >, 7 H T I, + KP, ?@'(?'@, @PP
= 7 ;/7, 5 W C % >U, W C d >;/7, 7 C 9; 5 > %, % / $ " "& " 0 & " G & " & H G Methylobacterium
extorquens % " %
* " >, , + ?N, KF?'(KF??, @PP'
= >8 9 , W " ( &H G &G )
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" , * . " 3= 7 J/7 , @PPE6 "
" " +. " + 3 > XW , @PP@C % 8 ;T 7 ,
@PPN C % 8 ;T 7 , @PPN C 5/7 8;9JD% > , @PPNC 5T , @PP 6
4 " " , Methylobacterium +
" " + , +
& A ) ! 39// , @PP?C % 8 ;T 7 , @PPFC
%/>C % 9;7;C $/>8 > 5 7, @PPEC 5/7 8;9JD% > , @PPNC 5T ,
@PP 6 3B/>>/;> B;98 C
> XW C JD9;75JT( 5 > 9, @PP C % 8 ;T 7 , @PPEC % 8 ;T 7 ,
@PP?6 Methylobacterium "
3 > /C >8//%, NMN6, * " "
35T , @PPF6,
" Quorum Sensing 3456 & : "
" (
45 " + * " " 0 <
" " " "
+ " ; " "
" ) " * " " "
+ , , , < " " +
" " .( " 3 D/>C
% 8/5;D5, @PPEC W ;7 , @PP?C 5 7 8/5( 7 >/> 5 , @PPKC 5 C
5 7WD#7C 9;= >/5, @PP?6 ) + +
" ( " , 45
+ + " ( 3 >7 > , @PPKC 5 7 8/5(
'?
45 + + 7( " (& " 3 89 6 "
" / " " " $ ( + * + +
" " , " " 0
& 3 >7 > , @PPKC 8 , NNMC %;99;C 559/>, @PP?C 9 8
, @PP@C 5 7 8/5( 7 >/> 5 , @PPKC S8; /C S;7 75, @PPK6 ,
* 89 " + ,
" , & + ! " 3 D/>C
% 8/5;D5, @PPE6
89 " !
Methylobacterium + 3@PP?6 " M. extorquens %
45 + 89 "
" " " - 0& , % & G 5 3@PPK6
" " 0 89 Methylobacterium .
.+ , 0 > " , 3@PPN6 0 * "
89 0 M. mesophilicum5> ?/?, " 3 > XW ,
@PP@6 " - ? 89 , 356(7(
3@/,KR6( " (859 356(7(3@/6( " (859, 0
+ 0 0 " 89
" " " $ ( + " ( " " M.
mesophilicum 5> ?/?, + " * " "
" " " " , " * , " + ! "
M. mesophilicum 5> ?/? " "
" 89 ) X. fastidiosa
7 , +. & ! 0 / " 2
" Pseudomonas aeruginosa, " + 89, * ? ?
" + ) " " ,
@@@ 3S $7/> C @PP'6 . A " " Sinorhizobium
meliloti + * 89 ) " +
) 3 8/7 , @PP'6 5"&H 0 3@PPK6 * >,
* + 0 P.
'K
/ Methylobacterium, +. & : "
" " 39// , @PP?C % 8 ;T 7 , @PPN C % 8 ;T 7
, @PPN C ;> ;9 , @PPPC 5T , @PP 6, " " & "
89 ) + + /
* " 89
3 /7\9=/> , @PP?6, *
" 0 " Methylobacterium 3 7 >/ / , @PP?6
7 , " - +
& * " & " "
" ( + " )
" ! " 3 $ J;C 9 8C S;99; 75, @PPMC
S 7$ , @P P6 5 , " " & "
) " " 7
" ) , 3@P P6 + ) + +
M. mesophilicum 5> ?/?( + " * +
& < , + " /
" , " " )
" < " , * "
" + +
= - " " ) M.
mesophilicum 5> ?/?, 2 + + , * >,
356(7( " (859 ) mxaB, acd5,crt;,pat, sss phoD,
+ + " "
4 7 &
7 />5 7, W C % >>;5, W C 7D77, 7 C 7 8 7T, C 9; 5 > %, % /
7 " * " & Methylobacterium extorquens % moxB moxW
+ + & ) $ NP ; 7 8 7T, !+ + % > 7
'M
7 >/ /, B C 9 = , C $ ;, 5 C > XW , S 9 C % 8/> 7;, S C = 7
=/> //J, 9 5 C = 7 /95 5, W C R/=/ , W 9 % G &
" H Methylobacterium mesophilicum Xylella fastidiosa
6 7 * " >@ H , + F@@ E N(E@?, @PP?
7 8 7T, C $8 58, % C 9 J/ , B & " " &
&G * " G * *
+ % 6 , 9 , + 'PE, ??F(?KE, NNE
> XW , S 9 C % > 7, W C % 8/> 7; WD7; >, S C = 7 /95 5, W C = 7
=DD> /, W S 9 C R/=/ , W 9 + G &G " " &
" H & Xylella fastidiosa " %
* " >, , + ?M, ENP?(EN E, @PP@
7/>W;, 5 C B9;/$/>, Patatin(9 I H G G " 0G
" _* " >, > , + FP, F@@(F@F, @PPE
7/>W;, 5 C D> 55, C B9;/$/>, & & & Legionella
pneumophilaO " ) , , & I " + "
0 6 7 * * " >, 8 , + @NM, ?N( M , @PPM >7 > , % 9 C S S7, 5 C D>>, C D9 8D>5 , 5 W C % 75 7, > / C
5 9% 7 , $ 4 , + " " G "
( " + + ! + 4 > > , 9 ,
+ '?@, ?F( M', @PPK
D/>, S C % 8/5;D5, D " *
2 >, 9 , + K, E@N(E'', @PPE
$ J;, C 9 8, J 8 C S;99; %5, J W /)
" H & & G(Pyrenophora "
" * + >, 9 , + N, ?EF(??P, @PPM
%;99;, C 559/>, 9 " ( " &H G ,
S & , + ' , '( ?, @PP?
8 , C $ , C 8/7, T C 58 S, C B >> 7 , 5 J " "G (
& " * ( G $ ( + ( "
" * * " 0 , 5 , + , N( @N, NNM
8/7$, C /77 7 , 5 % C RR > ;, J ; C /77/ (S , = C 8 > 9 7 ,
/ 9 C > ;75( > S7/, > % C D5 8/J, % & pst(phoD
" & " G G " & "Escherichia coli + "
'N
8/7, 8 C / 9; 5J;, % C > ;75 7, W C > 9B/, $ C D/>, S " G H ( G Sinorhizobium meliloti N( "G & "
* ( & G & 6 7
>, , + MF, FP@N(FP'?, @PP'
8;77 D> ;, C 9 8 7 >, C 5D7 > %, 5 & " 0 (
"G" ( (" )G " &G "
&G & " & &G / 6 7
* " > + >, ) , + @F, EP'( E , @PPN
> /, S C >8//%, 5 /" G & &G & " " +
" D * * " > >, , + ?@, @E'(@FP, NMN
D> , % 7 * +> " % @P P '@
3% $ " % & 6 O / " 5 "
Y9 0 4 0Z, D + 5 , " " , @P P
B/>>/;> B;98 , 5 C > XW , S 9 C JD9;75JT( 5 > 9, W " "
Methylobacterium " & ; 5;% e5;
;7 />7 ; 7 9 / ;7; ; [\ ;/7 ^B; D5 , " " 4 % R5
D5 , @PP
$9; J, > C > =; , C R >7T, W C 8/7$, R C D 7, W C %" 7J/T,
H & G " 4 8
, " > , + @?, @@K(@E@, @PPK
$ D>; 7, C B> 7 /R( 8 >9 , C = >8 9 , W &G> ; + + &
Methylobacterium extorquens % 6 7 >, , + ', P@K( P'F, @PPM
$>;5 S , C B;7/> 7, C /=/>5 7, 9 C S;99; %5 7, 7 > C 5 9% 7 ,
$ & & > H (" G " G & Serratia
& & * * " >, 9 , + @, MP( @, @PPN
8 > ;%, > C = 7 =/> //J, 9 5 C = 7 /95 5, W "
&G & H & ! * " >,
, + ?, P, E?'(EK , @PPM
W ;7 , ; " " + I , + 7/>
" % & & > G 5 " G K " @PPF 6 7 4 >
> 0 7 , 9 , + ', EFNOE?', @PP?
W D> 7 , C >/7;/>, C > ; >, 5 C B >; , 5 % C >;7, T C $ 9; 7 , C
$;> D , / C >/TBD5, > &G &G G H
Methylobacterium nodulans Crotalaria podocarpa * G* "
0 , 5 , + M, P? ( P?M, @PPF
EP
W;% , 5 C 5D$ 7D% , 7 C 5DRDJ;, C J;, C 8 T 58;, % C T J T % , C
8T % , C 5 %;RD, / C JDS , C 58; , C , 5 9 ( "
G ) G
,Lotus japonicus $1 4 +, IG , + , @?'(@KE, @PPE 9 = , C 9;, S C R/=/ , W 9 C 8 > D7$, W 5 > , " "
* + G & " & &G " " Methylobacterium
mesophilicum 6 7 * " > * + , , + ?F, F'F(
FE , @PP?
9 % > 8/, % $ C S 77/>, 9 C >1 ;75, 5 C 8 >/9, W & & & " + " H I " " & & &
& D * * " > 4 8, , + '@, E? (EK', @PPM
9//, 8 5 C % 8 ;T 7, % C J;%, S C 8 ;, 5 W C 8D7$, J T C 5 , %
&G " & " G H & " 3Oryza sativa9 6 G
" &G & 7@( ) &G & " > D >
7 , , + E@, EP@(EPM, @PP?
9;, T C R8 7$, T PhoD " H & + +
" " Escherichia coli % "
+ % + >, S & , + F , @PN@(@PNN, @PPK
9; 5 > %, % / C 8;5 5/> = , 9 & I G I " G
Methylobacterium 6 7 >, , + ME, M M, @PP'
9 8, W C >95 7, > S C T >J, S 5 C 5 /T, $ G ) , * "& "
+ + G " 1 , S & , + NN, EE O E?,
@PP@
9 9J/% , W 5 C 59 %, W & 2 " G &
" " 7 f( " 7 f( " *
* %" >, , + @F, F?K(FKP, @PPM
% " 7 9 , > C B 99, > " &
& & % + % ) ! , ) ,
+ @K, KPN( K ', NN'
% 8 ;T 7, % C 7$DR8 9;, 5 C 5/7 8;9JD% >, % C 5/58 >;, 5 C 8D7$,
8 T C T 7$, W C 5D7 > %, 5 C 5 , % $ H & "
G " " " " + P(EK 3Oryza sativa9 6 GMethylobacterium
7 % , , + EF, E, ' F('@E, @PPE
% 8 ;T 7, % C 7$DR8 9;, 5 C 9//, 8 5 C 5D 7 > %, 5 I(
" + &G & " " "" , H & G
" " M?P'@ 3Saccharum officinarum9 6 > D > 7 ,
E
% 8 ;T 7, % C 5D>/58 >/ T, = C 7 7 8 7, > C 5/7 8;9JD% >, % C
7$DR8 9;, 5 C 5D7 > %, 5 C 7$%;7 5 H &(
Methylobacterium " 3Arachis hypogaea 9 6
" H & & * " >, 7 H T I, + F', E, @KP(@K?,
@PP?
% 8 ;T 7, % C 7$DR8 9;, 5 C JS 7, 5 S C 5 , % Methylobacterium
phyllosphaerae 7 + , I( , " + &G & &
&G & " 0 6 7 > % >
* " >@> L " , + FN, @@(@K, @PPN
% 8 ;T 7, % C 7$DR8 9;, 5C 5/7 8;9JD% >, % C 5D7 > %, 5 C 5 ,
7 ( H & G &G & " " "
* " 4 +, , + ?E, E( @P, @PPN
7/%/ / J(% >58 99, % C % " 7 9 , > C B> 7R/7, W W C
S W ;/ 8 S5J;, 9 C B 99, > % & + / 0G " "
( & & & ) " " "
+ +> >, > "I+ , + PM, 'FN( '?M, NNF
7D77, 7 C T, C 7 8 7T, & " & &G
Methylobacterium extorquens % + % 6 , 9 , + @?P, MFK(
M?@, NMN
%/>, R 5 , % 9;7;, > , $/>8 > 5 7, " 0 G I(
" + &G & " " 3 B% 6 D * * " > >, , + E?, ' NO'@?, @PPE
/7\9=/>, $ 7 C % >;7, C 7 / , B C 5 D>/9, C %;9 7, C = >8 9 , W Methylobacterium extorquens % " + G "G &
" H & "& &G & " H & "
D , , + FMP, F? (F?K, @PP?
;> ;9 , % C 9 DJJ 7/7, 8 C 5 ;/ 8, 8 C %T99T9 , > C 8 8 9 ,
" " " & " "& 3 5G + 9 6 G
&G 0 % * " >, , + ??,
'PK'('PKK, @PPP
B BB9, % S H & " + * " ( > (
> 1 4 +, 9 , + @N, EF, @PP
7$DR8 9;, 5 C % 8 ;T 7, % C 5 , " "G (& "
* ( H ( + Methylobacterium 6 7
E@
%;7;, % C >DR, 9 > C $ ;, C > XW , S 9 C % >5 ; 9;, W 9 ( & "G (8 9 " Methylobacterium mesophilicum:5G &
6 7 1 , &, + K@, @ @ 'P(
@ 'E, @PPN
> % J/>5, C >D;W />, W % C 9/J 77/ / >/R, > 8 C % >% 7, B %
( G * + ( > 1 ,
, + ''N, ?@(??, @PP'
5 7 8/5( 7 >/> 5, % C D/>, S C $ , % C > ;75 7, W C S7;/,
4 ( & 0 G " " H &
+ + ! 7 !+ 4 > > , 9 , + '?@,
EN( ?', @PPK
5 7 % 77, $ /+ " & " "
&H G + 7 + % > +> , 7 H T I, + EM', ?N( KE,
@PPN
5 8S > R, C S 9 />, 5 C % > /7, 5 % C J;>5 88 B/>, B C 7D55/>, % C
5 , D D * + ( > ( > G & )
* ( Pseudomonas aeruginosa. >
> + % >, 8 , + 'MK, F '(F@ , @PPK
5 ;/>, % 8 + "& "
; 9/, > J 3/ 6 % " +> > 9 " " ,
NNM M ( '?
5/=/>;, / C 8 5;/, 8 B C 8 SJ8/ , W C 8 % 5, $ 8 & " 0
+ " " & G 35556 G + +
" H & I H " " " D * * " > ,
, + 'PE, EK(FE, @P P
5/7 8;9JD% >, % C % 8 ;T 7, % C 5D7 > %, 5 C J 77 ;T 7, 5
; " " 0 H & " Methylobacterium H &
( H & " 3Oryza sativa9 + (E'6 * " 4 +,
, + ?E, N@( PE, @PPN
5 , % W C 5 7WD#7, W C 9;= >/5, W >& 0 ( & " "
" " H * " >, 7 H T I, + F@, ' ?KO' KE, @PP?
5T, C $;> D , / C W D> 7 , C $ > ; , 7 C S;99/%5, C / 9 WD ;/, C >;7, T C 7/T> , % C $;99;5, % C ;=;7(% 55 7, C >/TBD5, % &G & "
Methylobacterium " ) G H & 6
E'
5T, C ;%%/>5, W C J7;/B, C = >8 9 , W % &G & "
+ Methylobacterium extorquens " 0 Medicago
truncatula " + " % * " >,
, + K , K@EF(K@F@, @PPF
T % , 8 C 7 8 7T, C 9; 5 > %, % / "
mxa Methylobacterium extorquens % G " D *
* " > , , + ??, (K, NNM
= 7 J/7, C />/5, % C T, 5 9 C T %, W % C 5 87 >, W 9
Methylobacterium populi nov, + ", I( , " + G
&G & ", & ( 0 " 3Populus
deltoides)nigra 7'E6 0 6 7 > % >
* " >@ I , + FE, N ( N?, @PPE
S $7/>, = / C D587/99, C 55 >, 9 C > J5, ; C ;$9/S5J;, 8
% " G G Pseudomonas aeruginosa* ( "
H & & + 6 7 >, , + MF, @PMP(
@PNF, @PP'
S 7$, U C 9;D, S C 8/7, U C 7$, C 7$, T C 8D 7$, U C S/;, $ C 8 7, 4 C
8D 7$, 9 C J 7$, R ) " " H
H& + G " 7 ( B9 " "
" * >, 9 , + P @P P +
a& //HHH " " / EK (@@@N/ P/N` " @@ @P P
S8; /, / S C S;7 75, 5 (" " " & &
Agrobacterium tumefaciens + + ! + 4 > > ,
9 , + '?@, 'F( EM, @PPK
UD, R C ; 7, C 5D7, R C 9;7, W C 8D , T ; " " G
&G & ) G " Deinococcus
radiodurans * " >, > , + F', ?F@( ?F@, @PPK
R8 7$, % C 9; 5 > %, % / " + + &
EE
I 21 0$ 4 9S D01 0
- " ( ,
) " & " " + + - ,
2 "
" " ! " " "
+ , " + +
+ " " / "
, ! Methylobacterium, * !
" " " A " *
" " " "
"& * X. fastidiosa " , Methylobacterium
* 0 < " " " , + *
+ " ,
Methylobacterium " , : " +
A "
7 & + * Methylobacterium
& + " " + ( )
" " - " " , " 4
0 " 0 , + *
+ + : "
+ " " " +
( ) 0 B + " * & + "
* * & + +
4 " " , +
" " . " " &
" ( , " + & +
"& " " + +
; ) " ! Methylobacterium <
" , * +
EF
Methylobacterium ! " " "
" " , + & + 0
" , : "
0 " , " " & &
".( & +
B + * M. extorquens > ?/@ )
" 3/ 6 " 0 " 0 & * " (
" " X. fastidiosa. , + *
0 , )
+ & Methylobacterium " ,
+ " " "
" "
" " * Methylobacterium
" & , + * ) mxaB,
acd5, crt;, pat, sss phoD M. mesophilicum 5> ?/?
356(7( " (859 7 " ) , + * ,
" - + , 89 " +
mxaB, " " " "
C pat, * " " + + " +
" 0 C acd5, "
+ & , * "
+ " " + + " @, M.
mesophilicum 5> ?/? + " " " , , +
* " " < + acd5
& ) crt;,phoD sss 89
" - + , * " " +
" "
" +
-89 Methylobacterium
+ " , &. - " (
E?
+ - , " & +
" + + Methylobacterium( , "
" - . " " " , + * "
< " " ,
" + " Methylobacterium " "
" " + , " , ,
