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Cell Treatment for Stroke in Type Two Diabetic Rats Improves Vascular Permeability Measured by MRI.

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Fig 1. Quantitative measurements of MRI. Temporal traces of the ischemic lesion volumes demarcated from T 2 maps (A) were close and no significant differences (p>0.05) were detected after stroke, between the BMSC and saline treated T2DM rats
Fig 2. Evolution of BBB disruption by MRI. BBB disruption, with enhancement in the subtracted images of pre and post gadopentetate of CE-T1WI, persisted from 1w to 5w post stroke in saline treated, i.e., control, T2DM rat (C, the top row)
Fig 4. Histology of BBB disruption and hemorrhage. With the histological H&E stained sections under the light microscope, hemorrhage was found with more red cells and more diffusively distributed in the ischemic cerebral tissue in the control T2DM rat
Fig 5. Mismatch of BBB disruption and hemorrhage. The locations of BBB disruption with high permeability K i values of gadopentetate and the spots of hemorrhage with hypointensity of SWI, were found overlapped (A1 & A2), dislocated (B1 & B2), i.e.,

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