Lapatinib induces autophagy, apoptosis and megakaryocytic differentiation in chronic myelogenous leukemia K562 cells.

In summary, results showed that aqueous HUANG-LIAN inhibited cell proliferations by inducing apoptosis and cell-cycle arrest in A549 breast cancer cells. These

Autophagy inhibition promotes 5-fluorouraci- induced apoptosis by stimulating ROS formation in human non-small cell lung cancer A549 cells. Targeting autophagy augments in vitro

Indeed, a de- ficiency in IL-6 alters the balance between the proliferation and differentiation of progenitor cells of the granulocytic- monocytic, megakaryocytic and erythroid

In this chapter we analysed genotoxicity in K562 c ells with the comet assay and the γ -H2AX assay and evaluate the mechanisms of apoptosis and cell survival in human chronic

Silencing of augmenter of liver regeneration inhibited cell proliferation and triggered apoptosis in U266 human multiple myeloma

In conclusion, we found that endothelial cells were mediated in the abnormal differentiation of Th subsets, and adiponectin inhibited the differentiation of Th1 and Th17 subsets

umbella- tum is cytotoxic to human leukemia cells, promoting cell growth inhibition and inducing death via apoptosis by an increase in ROS generation, alterations in mitochondrial

Methods: We examined the cytotoxic and pro-apoptotic effect of MjTX-I in K562-S and K562-R Bcr-Abl + cells and in the non-tumor HEK-293 cell line and peripheral blood mononuclear