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I-FABP as biomarker for the early diagnosis of acute mesenteric ischemia and resultant lung injury.

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Academic year: 2017

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Fig. 1. Survival and intestinal injury following acute mesenteric ischemia and reperfusion
Fig. 2. I-FABP as novel biomarker for ischemia/reperfusion injury. A , Plasma intestinal (I)-FABP, measured via ELISA, was found to be significantly elevated after ischemia at all time points compared to sham animals (n 5 3, 4, 4, 4, 5 for sham, 0.5, 1, 2
Fig. 3. Distant organ injury – increased lung MPO and injury. A , MPO on lung homogenates illustrated increased activity after 1, 2, and 3 h intestinal ischemia compared to sham treated mice (n 5 4 for all groups)
Fig. 4. Increased lung inflammation following intestinal ischemia/reperfusion. Lung homogenates were used to measure inflammatory chemokines and cytokines
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