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Tissue-specific effects of genetic and epigenetic variation on gene regulation and splicing.

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Academic year: 2017

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Table 1. Summary of associations and allele-speci fi c expression analyses in GenCord.
Figure 1. Enrichment of eQTLs and mQTLs in distinct genomic regions. For distinct genomic regions, the proportion of overlapping eQTLs (A) and mQTLs (B) (both in red) was compared to the proportion of overlapping null SNPs (black, see Methods for details)
Table 2. π 1 statistic representing fraction of effects shared between cell-types. significant in—π 1 of P-value distribution in
Figure 2. Cell-type specific genetic effects on gene expression and DNA methylation. Effect sizes of expression Quantitative Trait Locus (eQTL) (A) and methylation QTLs (mQTL) (B) unions for each pair of cell-types
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