An in silico analysis of the binding modes and binding affinities of small molecule modulators of PDZ-peptide interactions.

In contrast, Dp260 lacks the cytokeratin filament–binding domain and portions of the synemin­ and actin­ binding domains, which likely alters the binding affinities to both

The validity of the concepts of redundancy between HS sequences and activity, and the effects of cations on their binding properties is illustrated by the binding profiles of

The stare decisis doctrine in the United States legal culture requires that oncean appellate court in the State or federal judicial system has selected a principle

The basic principles of X-ray Crystallography and Nuclear Magnetic Resonance (NMR), the techniques used in the structural characterization of these proteins, are

Analysis of docking results and correlation with an- timalarial activity - Binding affinities of docked com- pounds were scored with Surflex-Dock scoring function and the

the binding process and to distinguish the binding modes is the combination of absorption spectroscopy detecting the total concentration of adsorbed on DNA molecules and

All inhibitors were subsequently docked into the binding site obtained from the receptor and conformation of the inhibitors with the lowest binding free energy was used to

was performed to corroborate the experimental results, by predicting the binding mode, relative binding energy of the complex formed between β -carboline derivatives with DNA and