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The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation.

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Academic year: 2017

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Figure 2. Histological analysis of Pik3c3 mutant embryos.
Figure 3. Pik3c3 mutant embryos lack mesoderm. A. Represen- Represen-tative images of in situ hybridization of Gata4, Hnf1 and Brachyury in control and Pik3c3 mutant embryo sections at E6.5
Figure 4. No apoptotic cell death but reduced proliferation in Pik3c3 mutant embryo. A

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