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Comparative 3'UTR analysis allows identification of regulatory clusters that drive Eph/ephrin expression in cancer cell lines.

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Academic year: 2017

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Table 2. Motifs in biotinylated probes used for RNA-protein pulldown assay and binding patterns of AUF1 (p42/p45) and HuR.
Figure 6. HuR regulates expression of Eph/ephrins. HuR was knocked down with a specific HuR RNAi oligonucleotide in HeLa and U373 cells (A) mRNA expression of EfnA2, EphA2 and EphA4 72 hours after transfection of a specific HuR RNAi oligo was compared to t
Figure 7. HuR is a direct regulator of Eph/ephrin mRNA stability. (A) 48 hours after transfection of a specific HuR RNAi oligonucleotide or a control oligonucleotide the half-lives of EfnA2, EphA2 and EphA4 mRNAs were assessed by using 5 mg/ml Actinomycin

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