Characterization of the Arabidopsis thaliana E3 ubiquitin-ligase AtSINAL7 and identification of the ubiquitination sites.

Human Scribble (Vartul) Is Targeted for Ubiquitin- Mediated Degradation by the High-Risk Papillomavirus E6 Proteins and the E6AP Ubiquitin- Protein Ligase. A strategy for

To determine whether the E3 ubiquitin ligases were capable of promoting Glis3 ubiquitina- tion as a result of their interaction, FLAG-Glis3 or the PY 461 mutant was co-expressed

We have demonstrated here that TRIM21 is tyrosine phosphorylated only in this domain indicating a possible role for the tyrosine phosphorylation of TRIM21 regulating its ability to

An accumulation of SUMO chains also causes the extreme genome instability and cell cycle phenotypes of fission yeast that lack the SUMO-targeted E3 ubiquitin ligase (STUbL) Slx8-Rfp1

A previous study of structural disorder in the human ubiquitin-proteasome system found evidence for disorder in E1, E2 and—to the greatest extent—E3 enzymes, and provided examples

Both p62 and ubiquitin were recruited to mycobacteria in DC2.4 cells transfected with Atg5 siRNA, but the depletion of p62 decreased the ubiquitination of mycobacteria in these

Taken together, our data demonstrate that cIAP1 and cIAP2 are direct E3 ubiquitin ligases for all four RIPs and indicate that cIAP1 conjugates RIP1–4 with diverse types of

Recent- ly, GRAIL (the E3-ubiquitin ligase gene related to anergy in lymphocytes) was shown to be responsible for the Th2 hypore- sponsiveness in a mouse model of