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The emergence of YMDD mutants precedes biochemical flare by 19 weeks in lamivudine-treated chronic hepatitis B patients: an opportunity for therapy reevaluation

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Academic year: 2019

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Table 1. Biochemical and virologic response rates after 6, 12, and 18 months of lamivudine therapy.
Table 2. Virologic and biochemical findings among carriers of YMDD variants.
Figure 1. Biochemical breakthrough incidence (dotted line) and YMDD variant identification (full line) during lamivudine-based therapy.
Table 3. Time gap between YMDD variant identification and associated biochemical relapse in chronic hepatitis B patients under lamivudine therapy, reported by different investigators.

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