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Vascular endothelial growth factor-A enhances indoleamine 2,3-dioxygenase expression by dendritic cells and subsequently impacts lymphocyte proliferation

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Academic year: 2019

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Fig. 1A-H: expression of cell surface markers by human monocytes differentiated in vitro to dendritic cells (DCs) and cultured in the presence  of prostaglandin E2 + tumour necrosis factor alpha (PG-TNF) or Bacillus Calmette-Guérin (BCG) as maturation fact
Fig. 2: expression of vascular endothelial growth factor (VEGF) receptors during human dendritic cell differentiation and subsequent matura- matura-tion in the presence of prostaglandin E2 + tumour necrosis factor alpha (PG-TNF) or Bacillus Calmette-Guérin
Fig. 4: transmission electron micrographs of monocytes and of den- den-dritic cells (DCs) matured with prostaglandin E2 + tumour necrosis  factor  alpha  (PG-TNF)  in  the  presence  or  absence  of  vascular   en-dothelial  growth  factor  (VEGF)
Fig. 6: T cell proliferation is impaired in the presence of dendritic cells (DCs) matured in the presence of vascular endothelial growth factor  (VEGF) lymphocytes were co-cultivated with autologous DC that were treated with VEGF in addition to prostagland
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