• Nenhum resultado encontrado

Dual role of respiratory syncytial virus glycoprotein fragment as a mucosal immunogen and chemotactic adjuvant.

N/A
N/A
Protected

Academic year: 2017

Share "Dual role of respiratory syncytial virus glycoprotein fragment as a mucosal immunogen and chemotactic adjuvant."

Copied!
10
0
0

Texto

Loading

Imagem

Figure 1. Expression and purification of recombinant G protein fragment, Gcf. (A) Deduced amino-acid sequence of the recombinant RSV G protein fragment (Gcf)
Figure 2. Characterization of humoral responses induced by Gcf immunization. (A) BALB/c mice were immunized twice on day 0 and day 14 with 20 mg of recombinant Gcf via indicated routes and serum IgG antibody titers specific for Gcf were measured by ELISA t
Figure 3. G-specific CD4 T-cell response in Gcf-immune mice. (A) Mice were immunized twice with Gcf s.l., once with FI-RSV by food-pad injection, or 16 10 5 PFU of live RSV A2 via i.n
Figure 5. Protective efficacy of mucosal vaccination with Gcf. Each group of immune mice was challenged with 16 10 6 PFU RSV A2 at 4 weeks after immunization and the levels of RSV replication in the lungs were determined by plaque assay at day 4 post chall

Referências

Documentos relacionados

Neste sentido, o presente estudo buscou aplicar a análise de agrupamentos para definir oportunidades de redução de custos na rede de distribuição de mel de uma

Respiratory syncytial virus (RSV) bronchiolitis is the most frequent cause of lower respiratory tract illness (LRTI) and hospitalization in young infants worldwide.. 1,2

3: temporal trend of sample positivity (indirect immunofluorescence) for respiratory syncytial virus, hospitalisation rates for RSV-associ- ated bronchiolitis and pneumonia,

respiratory syncytial virus infection in italian infants hospitalized for acute lower respiratory tract infections, and association between respiratory syncytial virus infection

Respiratory syncytial virus (RSV), one of the most important respiratory viruses, is responsible for annual epidemic ARI outbreaks in infants and pre-scholar children, worldwide

Methods— We analyze the relative burden of influenza, parainfluenza, respiratory syncytial virus (RSV), adenovirus and metapneumovirus, their seasonality and their association

Conclusion: Correlation between clinical phenotype and presence of LRV1 was not observed, although the frequency of the virus is two-fold higher in mucosal lesions than that found

Rapid detection of respiratory syncytial virus in nasopharyngeal aspirates by reverse transcription and polymerase chain reaction amplification. Detection of respiratory