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The antimicrobial activity of lapachol and its thiosemicarbazone and semicarbazone derivatives

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Academic year: 2019

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Fig. 1: synthesis of lapachol thiosemicarbazone and semicarbazone and structures of lapachol (A), lapachol derivatives thiosemicarbazone (B)  and semicarbazone (C).
Fig. 2 presents a perspective view of the lapachol thi- thi-osemicarbazone. The crystal data and refinement results  are listed in Table II
TABLE II
Fig. 3: molecular packing of lapachol thiosemicarbazone showing the  scheme of hidrogen bonding.

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