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Epigenetic biomarkers as predictors of clinical outcomes in colorectal cancer

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Academic year: 2021

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Figure 1.1 Hallmarks of cancer. Capabilities of tumor cells acquired during tumorigenesis (adapted  from Hanahan and Weinberg, 2011).
Figure 1.2 Schematic figure representing TGFβ signaling pathway. The activation of TGFβ  receptor induces proteins that inhibits cell cycle progression (from Tecalco-Cruz et al
Figure 1.4 Schematic figure representing the PI3K pathway. PI3K converts PIP2 into PIP3,  leading to the activation of AKT and Myc
Figure 1.5 Schematic figure representing Ras activation. The phosphorylation of RTK leads  to the activation of Ras (adapted from Schöneborn et al
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