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Orientador: Dora Maria Tuna de Oliveira Brites Investigadora Coordenadora e Professora Catedrática Convidada Faculdade de Farmácia, Universidade de Lisboa Co-orientador: Ana Sofia Iria Azeredo Falcão de Jesus Investigadora Auxiliar (Ciência 2007) Faculdad

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Academic year: 2019

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Fig. I.1  –  Classical view of neural stem cells hierarchy. The normal neural stem cell production of progenitor  cells,  which  subsequently  generates  the  three  differentiated  cell  types  of  the  central  nervous  system:  neurons,  oligodendrocyte
Fig. I.2  –  Gradual transformation of radial glial cells into astrocytes-like cells, from the embryonic period  to  adulthood
Fig. I.4  –  Schematic representation of  nanoparticles delivery by neural stem cells  inside a brain tumour
Fig.  I.5  –   Principal  feactures  and  phenotypes  of  neurospheres.  A)  Dead  cells  (red)  in  the  core  of  the  neurosphere (NS) are labeled with propidium iodide (PI) (red) and nuclei are counterstained with Hoechst 33342  (blue)
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