• Nenhum resultado encontrado

Homozygous Inactivating Mutation in NANOS3 in Two Sisters with Primary Ovarian Insufficiency

N/A
N/A
Protected

Academic year: 2017

Share "Homozygous Inactivating Mutation in NANOS3 in Two Sisters with Primary Ovarian Insufficiency"

Copied!
9
0
0

Texto

Loading

Imagem

Figure 1: A Mutational analysis of NANOS3 revealed a homozygous c.358G > A substitution in exon 1 in two sisters with primary amenorrhea.
Table 1: Polymorphic variants in NANOS3 identiied in POI patients and controls.
Figure 4: In silico analysis of amino acid interaction modiication shows the diferent conformation conferred by the p.Glu120Lys substitution.
Figure 5: Bulk representation of wild-type NANOS3, with p.Glu120Lys mutant shown in details box

Referências

Documentos relacionados

As doenças mais frequentes com localização na cabeça dos coelhos são a doença dentária adquirida, os abcessos dentários mandibulares ou maxilares, a otite interna e o empiema da

Katzmair (2018), que mapeou iniciativas, projetos, grupos, pessoas e insti- tuições em 92 países com relação direta a essas práticas, identificou ainda algumas semelhanças

Para determinar o teor em água, a fonte emite neutrões, quer a partir da superfície do terreno (“transmissão indireta”), quer a partir do interior do mesmo

-ATPase activity in the synaptic plasma membrane from cere- bral cortex of adult rats submitted to chronic administration of imipramine and fluoxe- tine.. We also studied the in vitro

In humans, we have shown the presence of a biologically active aromatase and of estrogen receptors ( α and ß) in ejaculated spermatozoa and in immature germ cells in.. addition

We examined in vitro the characteristics of embryonic cells of Rhipicephalus microplus and Amblyomma cajennense in cell culture and investigated the suitability of embryonic

Human serum is as efficient as fetal bovine serum in supporting proliferation and differentiation of human multipotent stromal (mesenchymal) stem cells in vitro and in

Transplantation of human embryonic stem cell-derived neural precursor cells and enriched environment after cortical stroke in rats: cell survival and functional