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Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA(2) Inhibition

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Academic year: 2017

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Figure 1. Effects of PrTX-I alone and PrTX-I pre-incubated with RA on indirectly evoked twitches in mouse phrenic-diaphragm preparations
Figure 3. Effect of RA upon the muscle damage index induced by PrTX-I in mouse diaphragm preparations
Figure 6. Comparison of the PrtX-I/RA complex with two other Lys49-PLA 2 s complexed to fatty acids
Figure 8. Model for Lys49-PLA 2 interaction with muscle membrane and the influence of RA

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